TrialPath

166 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

124 studies on the map

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) — 89bio Clinical Study Site, BirminghamA Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity — Advanced Cardiovascular, LLC, Alexander CityEvaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity — Alliance For Multispecialty Research - Daphne, DaphneMaridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity — University of Alabama Saint Vincent's Birmingham, BirminghamEASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease — Pinnacle Research Group, LLC, AnnistonA Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH — GSK Investigational Site, ArcadiaA Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH — 89bio Clinical Study Site, BirminghamA Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH — Akero Clinical Study Site, BirminghamLIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis — The Institute for Liver Health II DBA Arizona Clinical Trials, PeoriaA Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition — Arizona Liver Health, ChandlerA Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis — Akero Clinical Study Site, BirminghamA Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH — GSK Investigational Site, ArcadiaLIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis — University of Alabama at Birmingham, BirminghamA Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH) — Arizona Liver Health, ChandlerCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD) — Nephrology of North Alabama, DecaturPharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) — Phoenix Children's Hospital, PhoenixA Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH — Arizona Liver Health - Chandler, ChandlerA Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH) — Arizona Liver Health - Chandler, ChandlerFibrosis Lessens After Metabolic Surgery — Banner Health Center, PhoenixSotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — Stanford University Medical Center, StanfordEffect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT — Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center (The Lundquist Institute), TorranceSPYRAL GEMINI Pilot Study — Stanford Hospital and Clinics, StanfordStudy to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH — University of California San Diego, La JollaDiet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease — Weill Cornell Medicine, New YorkA Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors — Site 108, ChandlerNon-Invasive Quantification of Liver Health in NASH (N-QUAN) — Arizona Liver Health, ChandlerCardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment — Fountains Family Care, ChandlerFeasibility of The Health Integrated Nutrition and Kidney Wellness Program — UPMC Kidney Clinic - Wexford, PittsburghFood and Fitness With Medicine (FFWM) — Ohio State Healthy Community Center, ColumbusVertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis — University of San Fransisco, San FranciscoEvaluation of Non-Invasive Tests for Metabolic Liver Disease — Clinical Pharmacology of Miami, MiamiTezspire Cardiac Events PASS — Healthcare Integrated Research Database (HIRD), WilmingtonSupporting Health in Veterans With Heart Failure — VA Clinic - Gainesville, GainesvilleCharacterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System — Hope Center, Washington D.C.A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH) — Arizona Liver Health, ChandlerA Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors — UConn Health, FarmingtonMilitary Health and Nutrition Examination Study — Fort Campbell, Fort CampbellA Study of Efimosfermin Alfa in Adults With Hepatic Impairment — GSK Investigational Site, RialtoAmerican Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study) — NIDDK-Phoenix Epidemiology and Clinical Research, PhoenixMechanisms of Semaglutide Therapy in Heart Failure Patients — Greenstone Biosciences, Palo AltoEffect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial — Brigham and Women's Hospital, BostonEndoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease — Brigham and Women's Hospital, BostonUnderstanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure — Johns Hopkins Center for Health Equity, BaltimoreQuantifying Hepatic Mitochondrial Fluxes in Humans — Texas Diabetes Institute - University Health System, San AntonioEndoscopic Ultrasound Shear Wave Elastography Study — Brigham and Women's Hospital, BostonAndrogens and NAFLD Longitudinal Cohort Study — University of California San Francisco, San FranciscoReversal of Lipid-Induced Insulin Resistance — Magnetic Resonance Research Center (MRRC), New HavenPredicting Outcomes in Nonalcoholic Steatohepatitis With Advanced Fibrosis — Mayo Clinic in Rochester, RochesterDigoxin In NASH (CODIN) — Yale New Haven Health, New HavenPharmacy-led Transitions of Care Intervention to Improve Medication Adherence — University of Tennessee Medical Center, KnoxvilleHome Hospital for Suddenly Ill Adults — Brigham and Women's Hospital, BostonMindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF — VA Boston, BostonAI Platform for Fatigue and Depression Detection — Indiana University, IndianapolisImpact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD) — Cincinnati Children's Hospital Medical Center, CincinnatiCARBON: UAB Cardiovascular Research Biobank — University of Alabama at Birmingham, BirminghamGut Microbiota in Metabolic Surgery — Vanderbilt_University MC, NashvilleTime-restricted Eating and Healthy Eating in Patients With Metabolic Liver Disease or Cancer — University of California San Diego, La JollaWatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time — Arizona State University, TempeThe Weight of Cardiovascular Disease — Mayo Clinic in Rochester, RochesterRole of Adiposomes in Endothelial Dysfunction — University of Illinois at Chicago, ChicagoMetabolic Effects of Angiotensin-(1-7) — Vanderbilt University Medical Center, NashvilleThe Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health — University of California, Davis, DavisImpact of Lean Pork on Endothelial Function in Perimenopause — Pennington Biomedical Research Center, Baton RougeGENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study — University of Alabama at Birmingham, BirminghamPioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants — Texas Diabetes Institute/UH, San AntonioInvestigating the Link Between Type 2 Immunity and NAFLD in Human Obesity — Mayo Clinic in Arizona, ScottsdaleIntermittent Fasting for NAFLD in Adults — Massachusetts General Hospital, BostonCommunity Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study — Miami-Dade County Parks, Recreation and Open Spaces Department, MiamiPathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) — Yale New Haven Hospital, New HavenInspire HER: Inspiring the Heart and Emotions for Radical Health — University of Alabama at Birmingham, BirminghamNew Heart Imaging Techniques to Evaluate Possible Heart Disease — National Institutes of Health Clinical Center, BethesdaAssociations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status — UVA Student Health and Wellness Building, CharlottesvilleAdapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics — Washington University in St. Louis, St LouisEvaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics — Washington University in St. Louis, St LouisSympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) — University of Kansas Medical Center, Kansas CityEarly Tracking of Childhood Health Determinants (ETCHED) Study — NIDDK, Phoenix, PhoenixEffects of Whole vs. Nonfat Milk Consumption on Body Composition in Children — New Balance Foundation Obesity Prevention Center, BostonPRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis — University of Alabama at Birmingham, BirminghamEffects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults — University of Texas Health Science Center at San Antonio, San AntonioRoutine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) — University of Missouri-Columbia, ColumbiaTriage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility — Brooklyn Clinical Research, BrooklynBlack Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention — The Ohio State University, ColumbusHarnessing Macrophage Lysosomal Lipid Metabolism in Obesity — University of Missouri School of Medicine, ColumbiaHarnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM) — University of Missouri School of Medicine, ColumbiaBlood Collection Biorepository for Liver Disease Research — University at Buffalo, Buffalo General Medical Center, BuffaloEffect of Amino Acids on Hepatic Fat Content in Adolescents (AMINOS Study) — Univeristy of Colorado Anschutz Medical Campus, AuroraNT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study — University of Texas Southwestern Medical Center, DallasLifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients — West Virginia School of Osteopathic Medicine, LewisburgMitigation of Cardiovascular Disease Risks in Children With Extreme Obesity — University of Kentucky, LexingtonEVOC - EVs in Obesity and Cardiometabolic Disease — Massachusetts General Hospital, BostonLongitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance — Stanford University, StanfordThe Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity — University of Mississippi Medical Center, JacksonPrevention of Progression of Prediabetes, Obesity and CV Risk — University of Texas Health Science Center at San Antonio, San AntonioHIIT Effects on Cardiometabolic Health — Women's Building, SyracuseDiabetes and Heart Disease Risk in Blacks — National Institutes of Health Clinical Center, BethesdaNon-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health. — Clindove Research LLC, BrooklynHeart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention — National Institutes of Health Clinical Center, BethesdaAcute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes — University of Texas Health Science Center at San Antonio, San AntonioHuman Models of Selective Insulin Resistance: Alpelisib, Part I — Columbia University Irving Medical Center, New YorkEffect of Insulin Lowering on Lipogenesis — Columbia University Irving Medical Center, New YorkTargeting Breathing Limitations to Improve Functional Outcomes in HFpEF — UT Southwestern Medical Center, DallasImproving Coronary Vascular Health in Women — Massachusetts General Hospital, BostonImproving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads — University of South Carolina, ColumbiaLow-Dose Pioglitazone in Patients With NASH (AIM 2) — University of Florida, GainesvillePRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG — Metabolic Research Institute, Inc, West Palm BeachUsing Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes — UT Southwestern Medical Center, DallasClinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs — Poirot Podiatry, MetairieFiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF) — University of Michigan, Ann ArborNASH AMPK Exercise Dosing (AMPED) Trial — Penn State Hershey Medical Center, HersheyEvaluating the Pharmacokinetics and Safety of Miricorilant — Site# 433, San AntonioDevelopment of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis — University of Washington, SeattleRandomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant — Virginia Commonwealth University, RichmondMechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease — Ann & Robert H Lurie Children's Hospital of Chicago, ChicagoInAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer — Dana Farber Cancer Institute, BostonThyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans — Harry S. Truman Memorial, Columbia, MO, ColumbiaEffects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease — Henry Ford Health System, DetroitEstrogen Administration for the Treatment of NASH in Postmenopausal Women — Massachusetts General Hospital, BostonEvaluation of Miricorilant on Liver Fat in Patients With MASLD — University of Missouri, ColumbiaThermoacoustic Method for Estimating Liver Fat Fraction — ENDRA Life Sciences, Ann ArborThe Olmsted NAFLD Epidemiology Study (TONES) — Mayo Clinic in Rochester, RochesterRezdiffra Pregnancy and Lactation Registry — Madrigal Pharmaceuticals, West ConshohockenAccurate Point of Care Liver Disease Diagnostics (Phase 2) — University of California San Diego, La JollaBicalutamide Therapy in Young Women With NAFLD and PCOS — University of California San Francisco, San FranciscoAdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry (AVAIL) — AdventHealth Translational Research Institute, Orlando

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