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350 studies

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150 studies on the map

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) — Phoenix Children's Hospital, PhoenixStudy to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab — TG Therapeutics Investigational Trial Site, BirminghamEfficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. — Perseverance Research Center, ScottsdaleA Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia — Anaheim Clinical Trials, AnaheimPragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults — University of Alabama at Birmingham, BirminghamA Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis — Alabama Neurology Associates PC, BirminghamA Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) — TG Therapeutics Investigational Trial Site, BirminghamA Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH) — Arizona Liver Health - Chandler, ChandlerBest Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) — Stanford Multiple Sclerosis Center, Palo AltoTesting an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO — University of Alabama at Birmingham Cancer Center, BirminghamA Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2) — Local Institution - 0011, BirminghamA Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH) — Arizona Liver Health, ChandlerNon-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis — North Central Neurology Associates- Site Number : 8401100, CullmanA Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome — Clinical Research Institute of Arizona, Sun City WestA Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity — Alabama Neurology Associates, BirminghamA Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition — Arizona Liver Health, ChandlerSotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — Stanford University Medical Center, StanfordStudy to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH — University of California San Diego, La JollaA Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH — GSK Investigational Site, ChandlerA Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis — Arizona Neuroscience Research, LLC, PheonixSPYRAL GEMINI Pilot Study — Stanford Hospital and Clinics, StanfordOcrelizumab Discontinuation in Relapsing Multiple Sclerosis — Yale School of Medicine, New HavenA Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH — GSK Investigational Site, ArcadiaA Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH — GSK Investigational Site, ArcadiaStudy to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis — Local Institution - 0114, Loma LindaA Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis — Arizona Neuroscience Research, LLC, PhoenixA Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease — Knowledge Research Center, OrangeA Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH — Akero Clinical Study Site, BirminghamA Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS) — Profound Research, LLC, CarlsbadAn Open-label Study of AZD0120 in Adults With Multiple Sclerosis — Research Site, TucsonA Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors — Site 108, ChandlerMaridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity — University of Alabama Saint Vincent's Birmingham, BirminghamEASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease — Pinnacle Research Group, LLC, AnnistonA Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) — 89bio Clinical Study Site, BirminghamLIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis — University of Alabama at Birmingham, BirminghamA Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH — 89bio Clinical Study Site, BirminghamNon-Invasive Quantification of Liver Health in NASH (N-QUAN) — Arizona Liver Health, ChandlerThe SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study — Shepherd Center, AtlantaCare in Multiple Sclerosis (MS) — University of Alabama at Birmingham, BirminghamConfirmatory Trial for Alleviating Fatigue in Multiple Sclerosis — Washington VA Medical Center, Washington D.C.Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity — Alliance For Multispecialty Research - Daphne, DaphneLIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis — The Institute for Liver Health II DBA Arizona Clinical Trials, PeoriaA Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis — Akero Clinical Study Site, BirminghamA Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis — Stanford University Medical Center, StanfordA Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years — Boston Clinical Trials Inc - Internal Medicine, BostonA Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis — Profound Research, LLC, CarlsbadPredictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS) — Northwestern University, ChicagoA Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk — PROVIDE Virtual Research Coordination Center, San FranciscoA Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity — Advanced Cardiovascular, LLC, Alexander CityFibrosis Lessens After Metabolic Surgery — Banner Health Center, PhoenixA Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases — Stanford Neuroscience Health Center, Palo AltoGenes and Environment in Multiple Sclerosis — National Institute of Neurological Disorders and Stroke, BethesdaSupporting Health in Veterans With Heart Failure — VA Clinic - Gainesville, GainesvilleCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD) — Nephrology of North Alabama, DecaturEvaluation of Non-Invasive Tests for Metabolic Liver Disease — Clinical Pharmacology of Miami, MiamiVertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis — University of San Fransisco, San FranciscoA Study of Efimosfermin Alfa in Adults With Hepatic Impairment — GSK Investigational Site, RialtoProspective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod — University of Colorado Anschutz Medical Campus, AuroraCentral Vein Sign in Multiple Sclerosis Extension Study — Cedars-Sinai Medical Center, Los AngelesPregnancy Exposure Registry for Vumerity (Diroximel Fumarate) — University of Colorado Anschutz Medical Campus, AuroraStudy to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple Sclerosis — Minneapolis Clinic of Neurology, Golden ValleyCharacterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System — Hope Center, Washington D.C.Military Health and Nutrition Examination Study — Fort Campbell, Fort CampbellAmerican Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study) — NIDDK-Phoenix Epidemiology and Clinical Research, PhoenixSafety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers — UCSF, San FranciscoIMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy — Hospital for Special Surgery, New YorkMultiple Sclerosis Implementation Network (Registry) — Multiple Sclerosis Association of America, Cherry HillEffect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial — Brigham and Women's Hospital, BostonPredicting Outcomes in Nonalcoholic Steatohepatitis With Advanced Fibrosis — Mayo Clinic in Rochester, RochesterEndoscopic Ultrasound Shear Wave Elastography Study — Brigham and Women's Hospital, BostonAndrogens and NAFLD Longitudinal Cohort Study — University of California San Francisco, San FranciscoTargeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis — Johns Hopkins University, BaltimoreHigh-Intensity, Dynamic-stability Gait Training in People With Multiple Sclerosis — Rehabilitation Hospital of Indiana, IndianapolisTreatment of Participants With Primary or Secondary Progressive Multiple Sclerosis — University of Kansas Medical Center, Kansas CityObe-cel in Refractory Progressive Forms of Multiple Sclerosis — Stanford University, Redwood CityFeasibility of The Health Integrated Nutrition and Kidney Wellness Program — UPMC Kidney Clinic - Wexford, PittsburghCardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment — Fountains Family Care, ChandlerA Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH) — Arizona Liver Health, ChandlerFood and Fitness With Medicine (FFWM) — Ohio State Healthy Community Center, ColumbusTezspire Cardiac Events PASS — Healthcare Integrated Research Database (HIRD), WilmingtonA Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors — UConn Health, FarmingtonMechanisms of Semaglutide Therapy in Heart Failure Patients — Greenstone Biosciences, Palo AltoSocial Needs Screening and Chronic Diseases Study (WE CARE) — UMass Memorial Medical Center - Hahnemann Campus, WorcesterA Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring — Evidera INC., BethesdaPrepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS? — Jacobs School of Medicine and Biomedical Sciences, Neurology, University at Buffalo, BuffaloUnderstanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure — Johns Hopkins Center for Health Equity, BaltimoreRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford — Sanford Health, Sioux FallsEndoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease — Brigham and Women's Hospital, BostonAddressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US — Duke University - Charlotte Study Sites, CharlotteQuantifying Hepatic Mitochondrial Fluxes in Humans — Texas Diabetes Institute - University Health System, San AntonioDigoxin In NASH (CODIN) — Yale New Haven Health, New HavenReversal of Lipid-Induced Insulin Resistance — Magnetic Resonance Research Center (MRRC), New HavenPharmacy-led Transitions of Care Intervention to Improve Medication Adherence — University of Tennessee Medical Center, KnoxvilleHome Hospital for Suddenly Ill Adults — Brigham and Women's Hospital, BostonMindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF — VA Boston, BostonAI Platform for Fatigue and Depression Detection — Indiana University, IndianapolisA Palliative Care Model Impact on Knowledge and Attitudes — Judith Jaffe Multiple Sclerosis Center, New YorkWearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study — Norman Fixel Institute for Neurological Diseases, GainesvilleEffects of Ublituximab on Motor Functions in Multiple Sclerosis — Georgia State University, AtlantaBlood Collection Biorepository for Liver Disease Research — University at Buffalo, Buffalo General Medical Center, BuffaloTriage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility — Brooklyn Clinical Research, BrooklynGENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study — University of Alabama at Birmingham, BirminghamHealthy Living Anson Study — University of North Carolina at Chapel Hill, Chapel HillGut Microbiota in Metabolic Surgery — Vanderbilt_University MC, NashvilleLifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients — West Virginia School of Osteopathic Medicine, LewisburgHeart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention — National Institutes of Health Clinical Center, BethesdaIntermittent Fasting for NAFLD in Adults — Massachusetts General Hospital, BostonWatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time — Arizona State University, TempePRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis — University of Alabama at Birmingham, BirminghamThe Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health — University of California, Davis, DavisMetabolic Effects of Angiotensin-(1-7) — Vanderbilt University Medical Center, NashvilleIntermittent Cottonseed Oil Consumption — University of Georgia, AthensMitigation of Cardiovascular Disease Risks in Children With Extreme Obesity — University of Kentucky, LexingtonHuman Models of Selective Insulin Resistance: Alpelisib, Part I — Columbia University Irving Medical Center, New YorkInspire HER: Inspiring the Heart and Emotions for Radical Health — University of Alabama at Birmingham, BirminghamPioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants — Texas Diabetes Institute/UH, San AntonioLiver Adiposity Effects on Pediatric Statin — Children's Mercy Hospital, Kansas CityTargeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial — Sidney & Lois Eskenazi Hospital, IndianapolisCommunity Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study — Miami-Dade County Parks, Recreation and Open Spaces Department, MiamiNon-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health. — Clindove Research LLC, BrooklynPilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food — Cambridge Health Alliance, SommervilleHIIT Effects on Cardiometabolic Health — Women's Building, SyracuseSympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) — University of Kansas Medical Center, Kansas CityAdapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics — Washington University in St. Louis, St LouisEffect of Insulin Lowering on Lipogenesis — Columbia University Irving Medical Center, New YorkEarly Tracking of Childhood Health Determinants (ETCHED) Study — NIDDK, Phoenix, PhoenixPrescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults — Kennesaw State Universityh, KennesawHarnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM) — University of Missouri School of Medicine, ColumbiaHarnessing Macrophage Lysosomal Lipid Metabolism in Obesity — University of Missouri School of Medicine, ColumbiaEvaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics — Washington University in St. Louis, St LouisEffects of Whole vs. Nonfat Milk Consumption on Body Composition in Children — New Balance Foundation Obesity Prevention Center, BostonRoutine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) — University of Missouri-Columbia, ColumbiaThe Weight of Cardiovascular Disease — Mayo Clinic in Rochester, RochesterTargeting Breathing Limitations to Improve Functional Outcomes in HFpEF — UT Southwestern Medical Center, DallasCottonseed Oil Versus Matched PUFA Effects — University of Georgia, AthensEVOC - EVs in Obesity and Cardiometabolic Disease — Massachusetts General Hospital, BostonPrevention of Progression of Prediabetes, Obesity and CV Risk — University of Texas Health Science Center at San Antonio, San AntonioDiabetes and Heart Disease Risk in Blacks — National Institutes of Health Clinical Center, BethesdaPathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) — Yale New Haven Hospital, New HavenPeople With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists — Northwestern Memorial Hospital, ChicagoNew Heart Imaging Techniques to Evaluate Possible Heart Disease — National Institutes of Health Clinical Center, BethesdaCARBON: UAB Cardiovascular Research Biobank — University of Alabama at Birmingham, BirminghamFELLAShip to Better Health — The Worship Center Cristian Church, BirminghamRole of Adiposomes in Endothelial Dysfunction — University of Illinois at Chicago, ChicagoBlack Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention — The Ohio State University, ColumbusLongitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance — Stanford University, StanfordThe Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity — University of Mississippi Medical Center, JacksonImpact of Lean Pork on Endothelial Function in Perimenopause — Pennington Biomedical Research Center, Baton RougeInvestigating the Link Between Type 2 Immunity and NAFLD in Human Obesity — Mayo Clinic in Arizona, ScottsdaleAssociations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status — UVA Student Health and Wellness Building, Charlottesville

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