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262 studies

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134 studies on the map

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma — Allervie Clinical Research, BirminghamA Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA) — Research Site, MobileBone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait — UConn Health, FarmingtonDownstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe Asthma — Duke University Medical Center, DurhamAchieving Understanding of the Natural History of Sickle Cell Trait (AUNT) — University of Alabama, BirminghamA Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) — University of Alabama at Birmingham, BirminghamAsthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study — University of Texas at Arlington, ArlingtonHospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care — Children's National Hospital, Washington D.C.A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma — AMR Clinical, TempeA Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma — Research Site, MontgomeryInnate Immunity in Allergic Asthma — University of Central Florida, OrlandoPromoting Asthma Management Guidelines With Technology-Based Intervention and Care Coordination in Clinics and Schools — Children's Hospital at Montefiore, Albert Einstein College of Medicine, The BronxEscalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease — National Institutes of Health Clinical Center, BethesdaAeviceMD for Detection of Wheeze in Pediatric and Adult Populations — Montefiore Medical Center, The BronxVitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up — Indiana University, IndianapolisPollution Intervention to Impact Kids Asthma Study — UPMC Children's Hospital of Pittsburgh, PittsburghVENTURI (VENTilation Using Respiratory Imaging) — The University of Alabama at Birmingham, BirminghamOptimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control — Nemours Children's Health, JacksonvilleENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults — Enveda Investigative Site, BirminghamStress Management and Mindfulness Intervention for Patients With Sickle Cell Disease — University of Pennsylvania, PhiladelphiaSMYLS Multi-site Trial — Medical University of South Carolina, CharlestonA Study of CDX-622 in Participants With Mild to Moderate Asthma — University of California, San Francisco, San FranciscoSickle Cell Improvement: Enhancing Care in the Emergency Department — Children's Wisconsin, MilwaukeeIntegrative Medicine in Pain Management in Sickle Cell Disease, 2.0 — Indiana University School of Medicine, IndianapolisA Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up — National Institutes of Health Clinical Center, BethesdaVerifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease — Cincinnati Children's Hospital Medical Center, CincinnatiA Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2) — Research Site 13, BakersfieldThe Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM) — UCSF Airway Clinical Research Center, San FranciscoSub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults — Harbor UCLA Medical Center, TorranceRandomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment — Research Site, ChandlerA Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma — Pfizer Clinical Research Unit - New Haven, New HavenComparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease — Children's of Alabama (MRD-HCT), BirminghamAdvancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease — Children's National Hospital, Washington D.C.The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease — University of Alabama at Birmingham- Site Number : 8400003, BirminghamFunctional Ovarian Reserve in Sickle Cell Disease — St. Jude Children's Research Hospital, MemphisUsing a Smart Inhaler to Support Asthma Management in Adolescents With Intellectual and Developmental Disabilities — Children's Hospital Los Angeles, Los AngelesA Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma — Velocity Clinical Research, Mobile, MobileDepemokimab Asthma Imaging and Bronchoscopy Sub-Study — GSK Investigational Site, BrooksvilleMindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease — University of Illinois Chicago, ChicagoMechanistic Insights From Bronchoscopy Airway Samples — University of California, San Francisco, San FranciscoBlood Sampling for Research Related to Sickle Cell Disease — National Institutes of Health Clinical Center, BethesdaMechanism(s) of Airflow Limitation During Exacerbation of Asthma — Arthur F Gelb Medical Corporation, LakewoodProtocol CAUSE-03 / CHEETAH — Children's Hospital Colorado: Allergy Program, AuroraTimely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation — Oklahoma Children's Hospital, Oklahoma CityPredictors of Pain in Sickle Cell Disease — Duke University Medical Center, DurhamSMART@Home Feasibility Trial — Cincinnati Children's Hospital Medical Center, CincinnatiA Real-World Registry of Chronic Wounds and Ulcers — US Wound Registry, The WoodlandsTechnology-Enhanced Asthma Care in Children at Clinic and Home Study — Ann & Robert H Lurie Children's Hospital of Chicago, ChicagoArginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease — Children's Healthcare fo Atlanta at Hughes Spalding, AtlantaATHNdataset Registry — American Thrombosis and Hemostasis Network, HickoryVirtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises — University of Maryland Medical Systems, BaltimoreObesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics — University of Colorado, AuroraHome Hospital for Suddenly Ill Adults — Brigham and Women's Hospital, BostonMetformin IN Asthma for Overweight and Obese Individuals (MINA) — Johns Hopkins University, BaltimoreTrans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease — Children's Hospital of Atlanta: Eagelston, AtlantaGenotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease — National Institutes of Health Clinical Center, BethesdaA Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma — Kymera Investigative Site, LancasterA Socio-ecological Approach for Improving Self-management in Adolescents With SCD — Nemours Children's Health, WilmingtonA Long-term Follow-up Study in Patients Who Received BEAM-101 — University of Alabama at Birmingham, BirminghamNutrition for Asthmatics — Pennington Biomedical Research Center, Baton RougeThe Allergen Reduction and Child Health Study (ARCHS) — Tulane University, New OrleansSickleFit Exercise and Nutrition Study — Duke University, DurhamHumidity Asthma Interventions for Low Socioeconomic Status Children — Case Western Reserve University, ClevelandA Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma — GSK Investigational Site, Newport BeachMetabolic and Hemodynamic Reserve in Pediatric SCA — Washington University in St. Louis, St LouisSchool Readiness Intervention for Preschool Children With Sickle Cell Disease — St. Jude Children's Research Hospital, MemphisRH Genotype Matched RBC Transfusions — Children's Hospital of Philadelphia, PhiladelphiaA Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease — University of Florida, Gainesville45th Multicenter Airway Research Collaboration — MetroHealth, ClevelandEfficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS) — Phoenix Children's Hospital- Site Number : 8400001, PhoenixLeveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping — Mayo Clinic, ScottsdaleSickle Cell, Pain and Mediterranean Diet — University of Illinois Chicago, ChicagoTransplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease — University of California, Los Angeles, Los AngelesIntegrative Training Program for Pediatric Sickle Cell Pain — Connecticut Children's Medical Center, HartfordAzithromycin for Critical Asthma - Pediatrics — Johns Hopkins All Children's Hospital, St. PetersburgEscitalopram in Asthma Patients With Frequent Exacerbation — UT Southwestern, 1440 Empire Central, Ste. LD4.100, DallasMULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease — UH Seidman Cancer Center Adult SCD Clinic or UH Rainbow Babies and Children's Hospital Sickle Cell Anemia Center, ClevelandCHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma — Affinia healthcare, 2220 Lemp Ave, St LouisCannabidiol in Sickle Cell Disease — Icahn School of Medicine at Mount Sinai, ManhattanDose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids — Research Site, BakersfieldMechanistic Study of Inspiratory Training in Childhood Asthma (MICA) — Duke Health Center Creekstone, DurhamNavigating Together for Equitable Asthma Management for Children in Families Who Communicate in Language Other Than English — Children's Hospital Colorado, AuroraThe Puerto Rico Asthma Integrated Response Program ("PR-AIR") — Rhode Island Hospital, ProvidenceCooperative Assessment of Late Effects for SCD Curative Therapies — Children's National Medical Center, Washington D.C.Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease — Boston Children's Hospital, BostonObservational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies — National Institutes of Health Clinical Center, BethesdaEarly Screening and Treatment of Heart Complication in Sickle Cell Disease — Inova Schar Cancer, FairfaxProphylactic Transfusion In Pregnant in Women With Sickle Cell Disease — Grady Health System, AtlantaStudy to Improve Deployment Related Asthma by Using L-Citrulline Supplementation — National Jewish Health, DenverUse of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects — Bensch Clinical Research LLC, StocktonZinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial — UCSF Benioff Children's Hospital Oakland, OaklandGene Editing For Sickle Cell Disease — St. Jude Children's Research Hospital, MemphisA Clinical Trial of Soluble Fiber for Asthma — Phoenix Children's, PhoenixAllo HSCT for High Risk Hemoglobinopathies — Masonic Cancer Center, MinneapolisRecruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease — University of Alabama, Birmingham (UAB), BirminghamAcoustic Waveform Respiratory Evaluation — Indiana University, IndianapolisStudy of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease — Site # 8400006, AtlantaApplying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness — Lurie Children's Hospital, ChicagoA Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1) — Research Site 23, NorthridgeExercise in Child Health — University of California, Irvine, IrvineBody Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry — University of Rochester Medical Center, RochesterClinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU — Brigham and Women's Hospital, BostonComparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline — Massachusetts General Hospital, BostonA Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice — Clinical Research of California - Site Number: 840145, Walnut CreekTelehealth-Enhanced Asthma Care for Home After the Emergency Room — University of Rochester Medical Center, RochesterProject ASTHMA - Aligning With Schools To Help Manage Asthma and Improve Outcomes — University at Buffalo, Department of Pediatrics, BuffaloVentilation and Perfusion in Asthmatics — University of Miami - Converge Miami, MiamiThe Airports, Air Quality, and Asthma (AAA) Study — University of Washington, SeattleComparison of Microglial Activation in Severe Asthma and Healthy Controls — Center for Healthy Minds, MadisonTelehealth and Onsite Maintenance Exercise in Chronic Lung Disease — MGH Institute of Health Professions, CharlestownPeripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease — St. Jude Children's Research Hospital, MemphisA Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) — Memorial Sloan Kettering at Basking Ridge (Consent only), Basking RidgeA Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — Univ of Alabama Birmingham, BirminghamAsthma Symptom Perception Study — Ichan School of Medicine at Mount Sinai, New YorkA Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease — University of Alabama at Birmingham, BirminghamImpact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology — UCSF Airway Clinical Research Center, San FranciscoEvaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma — Research Site, AnchorageDetermination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling — National Institutes of Health Clinical Center, BethesdaStudy to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease — National Institutes of Health Clinical Center, BethesdaPartial Stem Cell Transplant for Sickle Cell Disease From Matched Donors — National Institutes of Health Clinical Center, BethesdaStudy to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease — National Institutes of Health Clinical Center, BethesdaHematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies — Boston Children's Hospital, BostonTargeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin — University of Illinois Chicago, Sickle Cell Center, ChicagoSickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody — Children's National Hospital, Washington D.C.Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity — Columbia University Irving Medical Center, New YorkPeer Support for Adolescents and Emerging Adults With Sickle Cell Pain — University of South Alabama Medical Center, MobileAsthma Link Effectiveness Trial — University of Massachusetts Chan Medical School, WorcesterA Feasiblity Study of Green Activity Program for People Living With Memory Challenges — Indiana University Bloomington, BloomingtonSMART Implementation-Effectiveness Trial 1 — Children's Hospital of Philadelphia, PhiladelphiaSMART Implementation-Effectiveness Trial 2 — Children's Hospital of Philadelphia, PhiladelphiaFLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases — xCures, Los AltosSCD Stem Cell Mobilization and Apheresis Using Motixafortide — University of Alabama at Birmingham, BirminghamA Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) — University Of Alabama, BirminghamEffectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE) — Cincinnati Children's Hospital Medical Center, Cincinnati

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