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261 studies

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150 studies on the map

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) — Phoenix Children's Hospital, PhoenixA Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease — Uni of Alabama at Birmingham, BirminghamATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders — Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital, PhoenixA Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — Univ of Alabama Birmingham, BirminghamA Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA) — Research Site, MobileA Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma — Velocity Clinical Research, Mobile, MobileDose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids — Research Site, BakersfieldComparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease — Children's of Alabama (MRD-HCT), BirminghamEvaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma — Research Site, AnchorageA Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma — Research Site, MontgomeryA Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma — Kymera Investigative Site, LancasterA Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma — GSK Investigational Site, BirminghamA Long-term Follow-up Study in Patients Who Received BEAM-101 — University of Alabama at Birmingham, BirminghamThe Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease — University of Alabama at Birmingham- Site Number : 8400003, BirminghamA Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease — University of Alabama at Birmingham, BirminghamRandomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment — Research Site, ChandlerA Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) — University Of Alabama, BirminghamENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults — Enveda Investigative Site, BirminghamA Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma — AMR Clinical, TempeA Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1) — Research Site 23, NorthridgePeer Support for Adolescents and Emerging Adults With Sickle Cell Pain — University of South Alabama Medical Center, MobileA Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma — Teva Investigational Site 12087, PhoenixEfficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS) — Phoenix Children's Hospital- Site Number : 8400001, PhoenixA Phase 2/3 Study in Adult and Adolescent Participants With SCD — Smilow Cancer Hospital, New HavenSafety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis — Univ. of California, San Francisco Health Care, OaklandIndividualizing Treatment for Asthma in Primary Care (Full Study) — DARTNet Institute, AuroraUse of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects — Bensch Clinical Research LLC, StocktonRecruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease — University of Alabama, Birmingham (UAB), BirminghamA Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma — Research Site, BakersfieldAchieving Understanding of the Natural History of Sickle Cell Trait (AUNT) — University of Alabama, BirminghamDepemokimab Asthma Imaging and Bronchoscopy Sub-Study — GSK Investigational Site, BrooksvilleRollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study — University Of Alabama, BirminghamA Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2) — Research Site 13, BakersfieldProtocol CAUSE-03 / CHEETAH — Children's Hospital Colorado: Allergy Program, AuroraRegistry of Asthma Characterization and Recruitment 3 (RACR3) — Children's Hospital Colorado: Allergy Program, AuroraA Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) — University of Alabama at Birmingham, BirminghamA Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease — University of Alabama Birmingham, BirminghamMinimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease — Children's National Health System, Washington D.C.Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial — UCSF Benioff Children's Hospital Oakland, OaklandSafety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD) — UAMS Medical Center, Little RockA Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma — GSK Investigational Site, Newport BeachStudy of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease — Site # 8400006, AtlantaSickle Cell Clinical Research and Intervention Program — Children's Hospital of Illinois at OSF-Saint Francis Medical Center, PeoriaGene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease — Children's Hospital Los Angeles, Los AngelesCooperative Assessment of Late Effects for SCD Curative Therapies — Children's National Medical Center, Washington D.C.A Study of CDX-622 in Participants With Mild to Moderate Asthma — University of California, San Francisco, San FranciscoA Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice — Clinical Research of California - Site Number: 840145, Walnut CreekMyeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease — University of California Los Angeles, Los AngelesA Socio-ecological Approach for Improving Self-management in Adolescents With SCD — Nemours Children's Health, WilmingtonRuxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease — Children's Hospital of Colorado, AuroraDelivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease — University of Illinois at Chicago, ChicagoReduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders — Yale School of Medicine, New HavenEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease — New York Presbyterian Hospital - Morgan Stanley Children's Hospital, New YorkIntegrative Training Program for Pediatric Sickle Cell Pain — Connecticut Children's Medical Center, HartfordLeveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping — Mayo Clinic, ScottsdaleApplying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness — Lurie Children's Hospital, ChicagoSCD Stem Cell Mobilization and Apheresis Using Motixafortide — University of Alabama at Birmingham, BirminghamA Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) — Memorial Sloan Kettering at Basking Ridge (Consent only), Basking RidgeReducing Overuse of Antibiotics With Decision Support — Benioff Children's Hospital - Oakland, OaklandAsthma and Technology in Emerging African American Adults — Florida State University, TallahasseeMetformin IN Asthma for Overweight and Obese Individuals (MINA) — Johns Hopkins University, BaltimoreAcoustic Waveform Respiratory Evaluation — Indiana University, IndianapolisPhase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma — Sun City Clinical Research, GlendaleVitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up — Indiana University, IndianapolisOptimizing a Sensor-Enabled mHealth Intervention for Adolescents With Suboptimal Asthma Control — Nemours Children's Health, JacksonvilleClinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease — Emory University, AtlantaMULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease — UH Seidman Cancer Center Adult SCD Clinic or UH Rainbow Babies and Children's Hospital Sickle Cell Anemia Center, ClevelandStudy of the Role of Genetic Modifiers in Hemoglobinopathies — Boston Children's Hospital, BostonReducing Asthma Attacks in Disadvantaged School Children With Asthma — Ault-Highland RE-9 school district, AultCHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma — Affinia healthcare, 2220 Lemp Ave, St LouisEffect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia — Magee Women's Hospital, PittsburghSocial Needs Screening and Chronic Diseases Study (WE CARE) — UMass Memorial Medical Center - Hahnemann Campus, WorcesterVerifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease — Cincinnati Children's Hospital Medical Center, CincinnatiMechanistic Study of Inspiratory Training in Childhood Asthma (MICA) — Duke Health Center Creekstone, DurhamSickle Cell Kidney Biorepository — Parkland Memorial Hospital, DallasHome Hospital for Suddenly Ill Adults — Brigham and Women's Hospital, BostonSite and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap — Arthur F Gelb MD, LakewoodHumidity Asthma Interventions for Low Socioeconomic Status Children — Case Western Reserve University, ClevelandSoy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study — Ann and Robert H Lurie Childrens Hospital of Chicago, ChicagoBREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma — Sun River Health, BeaconAsthma Symptom Perception Study — Ichan School of Medicine at Mount Sinai, New YorkPersonalized Environment and Genes Study — University of North Carolina, Chapel HillThe Puerto Rico Asthma Integrated Response Program ("PR-AIR") — Rhode Island Hospital, ProvidenceY of Central Maryland Head Start Asthma Implementation — Easter Seals Head Start Prince George's County, District HeightsRole of Genetic Factors in the Development of Lung Disease — Suburban Hospital, BethesdaAsthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study — University of Texas at Arlington, ArlingtonArginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease — Children's Healthcare fo Atlanta at Hughes Spalding, AtlantaTransplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease — University of California, Los Angeles, Los AngelesEarly Screening and Treatment of Heart Complication in Sickle Cell Disease — Inova Schar Cancer, FairfaxEffect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease — Methodist Comprehensive Sickle Cell Center, MemphisObesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics — University of Colorado, AuroraSupplementing L-citrulline to Overweight Late Asthma oNset Phenotypes — Duke University (Asthma, Allergy and Airway Center), DurhamAnti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma — University of Colorado Anschutz Medical Campus, AuroraBody Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry — University of Rochester Medical Center, RochesterComparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline — Massachusetts General Hospital, BostonInspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma — Duke Healthy Lifestyles Clinic, DurhamMechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma — Arthur F Gelb Medical Corporation, LakewoodThe Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser) — Biomechanics Research Building, OmahaThe Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM) — UCSF Airway Clinical Research Center, San FranciscoClinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU — Brigham and Women's Hospital, BostonAeviceMD for Detection of Wheeze in Pediatric and Adult Populations — Montefiore Medical Center, The BronxHyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease — University of Kansas Medical Center, Kansas CityTelehealth and Onsite Maintenance Exercise in Chronic Lung Disease — MGH Institute of Health Professions, CharlestownMechanism(s) of Airflow Limitation During Exacerbation of Asthma — Arthur F Gelb Medical Corporation, LakewoodEvaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease — University of Kansas Medical Center, Kansas CityUsing a Smart Inhaler to Support Asthma Management in Adolescents With Intellectual and Developmental Disabilities — Children's Hospital Los Angeles, Los AngelesTelehealth-Enhanced Asthma Care for Home After the Emergency Room — University of Rochester Medical Center, RochesterViral Infection in Asthma (VIA) Study — University of Virginia, CharlottesvilleThe Allergen Reduction and Child Health Study (ARCHS) — Tulane University, New OrleansVENTURI (VENTilation Using Respiratory Imaging) — The University of Alabama at Birmingham, BirminghamMicroglia Activation in Asthma — University of Wisconsin Madison, MadisonImpact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology — UCSF Airway Clinical Research Center, San FranciscoDownstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe Asthma — Duke University Medical Center, DurhamNutrition for Asthmatics — Pennington Biomedical Research Center, Baton RougeSpirometric Response to Bronchial Thermoplasty in Patients With Severe Asthma — OUHSC, Oklahoma CityThe Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic — Children's National Hospital, Washington D.C.NHALES (Natural History of Asthma With Longitudinal Environmental Sampling) — NIEHS Clinical Research Unit (CRU), Research Triangle ParkSMART Implementation-Effectiveness Trial 2 — Children's Hospital of Philadelphia, PhiladelphiaA Long-term Study of KT-621 Administered Orally to Participants With Asthma Previously Enrolled in a KT-621 Asthma Study — Kymera Investigative Site, TampaWearable Electronic Breath Sound Sensing Device — Arthur M. Blank Hospital | Children's Healthcare of Atlanta, AtlantaImpact of Sleep Duration on Immune Balance in Urban Children With Asthma — Rhode Island Hospital, ProvidencePollution Intervention to Impact Kids Asthma Study — UPMC Children's Hospital of Pittsburgh, PittsburghTechnology-Enhanced Asthma Care in Children at Clinic and Home Study — Ann & Robert H Lurie Children's Hospital of Chicago, ChicagoASTHMAXcel Voice Study — Montefiore Medical Center, The BronxViral Mucosal Reprogramming — University of Texas Medical Branch, GalvestonImplementation of Asthma Community Home and School Management Program (Asthma CHAMPS) — Baltimore City Public Schools, BaltimoreCost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity — Columbia University Irving Medical Center, New YorkReslizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA) Study — National Jewish Health, DenverStudy of the Effect of Innate on the Inflammatory Response to Endotoxin — NIEHS Clinical Research Unit (CRU), Research Triangle ParkSMART@Home Feasibility Trial — Cincinnati Children's Hospital Medical Center, Cincinnati5HTP Regulation Of Asthma In Children — Indiana University, IndianapolisFeasibility of a Smartphone Application for Asthma Self-management — University of South Florida, TampaComparison of Microglial Activation in Severe Asthma and Healthy Controls — Center for Healthy Minds, MadisonHospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care — Children's National Hospital, Washington D.C.Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation — National Jewish Health, DenverA Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up — National Institutes of Health Clinical Center, BethesdaFood Allergy Registry at a Single Site — Stanford University, Palo AltoMechanistic Insights From Bronchoscopy Airway Samples — University of California, San Francisco, San FranciscoAsthma Link Effectiveness Trial — University of Massachusetts Chan Medical School, WorcesterA Clinical Trial of Soluble Fiber for Asthma — Phoenix Children's, PhoenixMeasuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma — The University of Pittsburgh Asthma Institute at UPMC, PittsburghPost-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age — Ann & Robert H. Lurie Children's Hospital of Chicago, ChicagoAction Towards Health Equity and Improved Air Quality in the Duwamish Valley: A Multilevel Asthma Intervention — Duwamish River Community Coaltion, SeattleProject ASTHMA - Aligning With Schools To Help Manage Asthma and Improve Outcomes — University at Buffalo, Department of Pediatrics, BuffaloThe Airports, Air Quality, and Asthma (AAA) Study — University of Washington, SeattleInnate Immunity in Allergic Asthma — University of Central Florida, Orlando45th Multicenter Airway Research Collaboration — MetroHealth, ClevelandA Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma — Pfizer Clinical Research Unit - New Haven, New HavenAzithromycin for Critical Asthma - Pediatrics — Johns Hopkins All Children's Hospital, St. PetersburgNavigating Together for Equitable Asthma Management for Children in Families Who Communicate in Language Other Than English — Children's Hospital Colorado, Aurora

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