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140 studies on the map

This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis. — Washington University in St. Louis, St LouisEvaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain — Shirley Ryan AbilityLab, ChicagoMindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF — VA Boston, BostonTreatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation — The University of Texas at Dallas, RichardsonA Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH) — Arizona Liver Health, ChandlerNAFLD Clinical Care Pathway — Michael E. DeBakey VA Medical Center, Houston, TX, HoustonEfficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. — Perseverance Research Center, ScottsdaleAI Platform for Fatigue and Depression Detection — Indiana University, IndianapolisNARCOMS Registry: A Multiple Sclerosis Registry — UT Southwestern Medical Center, DallasA Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH — GSK Investigational Site, ArcadiaThe Weight of Cardiovascular Disease — Mayo Clinic in Rochester, Rochester"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS — University of California, San Francisco, San FranciscoThe Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease — Brigham and Women's Hospital, BostonStudy to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab — TG Therapeutics Investigational Trial Site, BirminghamAdapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics — Washington University in St. Louis, St LouisA Single-Center Study to Characterize the Safety and Efficacy of Ublituximab in Older Adults With Relapsing Forms of Multiple Sclerosis (RMS) — Neurology Center of New England P.C., FoxboroughAn Open-label Study of AZD0120 in Adults With Multiple Sclerosis — Research Site, TucsonUblituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis — Northwestern Memorial Hospital, ChicagoSafety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial — AARA Clinical Research, GlendaleA Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors — UConn Health, FarmingtonEffect of Cooling on Balance Performance in Multiple Sclerosis — Hunter College, Physical Therapy Department, City University of New York, New YorkA Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus — Investigative Site, Beverly HillsEvaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis — National Institutes of Health Clinical Center, BethesdaDevelopment of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis — University of Washington, SeattleAndrogens and NAFLD Longitudinal Cohort Study — University of California San Francisco, San FranciscoA Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH) — Arizona Liver Health, ChandlerA Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases — Stanford Neuroscience Health Center, Palo AltoCD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus — Children's Hospital of Philadelphia, PhiladelphiaDalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis — MGH Institute of Health Professions, BostonA Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis — Stanford Multiple Sclerosis Center, Palo AltoUS Zamto-cel Autoimmune Diseases — Froedtert Hospital and the Medical College of Wisconsin, MilwaukeeDapagliflozin in Active Lupus Nephritis — Massachusetts General Hospital, BostonA Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2) — Inland Rheumatology Clinical Trials, Inc., UplandHome Based Functional Balance Intervention for Multiple Sclerosis — University of Illinois at Chicago, ChicagoNeuromodulating Cortical Regions Involved in Neurogenic Bladder in MS — Houston Methodist Hospital, HoustonA Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease — Research Site 4, Redwood CityWatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time — Arizona State University, TempeA Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity — Alabama Neurology Associates, BirminghamBringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients — University of Michigan, Ann ArborBreathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases — Mayo Clinic in Rochester, RochesterA Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 — University of Colorado, Denver, DenverA Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE) — Climb Bio Investigative Site #100104, AllenA Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis — Arizona Neuroscience Research, LLC, PheonixAcute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes — University of Texas Health Science Center at San Antonio, San AntonioA Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE) — Wallace & Lee Center, Beverly HillsSystemic Lupus Erythematosus in Gullah Health — Medical University of South Carolina, CharlestonResearch Accelerated by You Lupus Registry — Online Registry - No Physical Site Required, Washington D.C.Cutaneous Lupus Registry — University of Texas Southwestern Medical Center Dallas, DallasA Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1) — University of Colorado Anschutz Medical Campus, AuroraA Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS) — Profound Research, LLC, CarlsbadImpact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD) — Cincinnati Children's Hospital Medical Center, CincinnatiNew Heart Imaging Techniques to Evaluate Possible Heart Disease — National Institutes of Health Clinical Center, BethesdaEffect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial — Brigham and Women's Hospital, BostonA Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk — PROVIDE Virtual Research Coordination Center, San FranciscoDeciphering Preserved Autonomic Function After Multiple Sclerosis — Mayo Clinic, RochesterA Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants — Local Institution - 0062, MesaIConquerMS™ - a Patient-Powered Research Network for Multiple Sclerosis — Accelerated Cure Project, WalthamPathological Basis of MRI Signal Changes in Multiple Sclerosis — National Institutes of Health Clinical Center, BethesdaEffect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques — National Institutes of Health Clinical Center, BethesdaFall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters — Disability Participation and Quality of Life (DPQOL) Laboratory, UrbanaBest Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) — Stanford Multiple Sclerosis Center, Palo AltoBrief Pain Exposure Therapy (BPET) For Nociplastic Pain — University of Michigan, Ann ArborA Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis — Akero Clinical Study Site, BirminghamMaternal Autoimmune Disease Research Alliance (MADRA) Registry — Duke University, DurhamThe SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study — Shepherd Center, AtlantaHome Hospital for Suddenly Ill Adults — Brigham and Women's Hospital, BostonTrial of Belimumab in Early Lupus — Feinstein Institute, ManhassetThe Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study — University of California, San Francisco, San FranciscoCereset Research Exploratory Study — Wake Forest University Health Scienc\ess, Winston-SalemNon-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES) — National Institutes of Health Clinical Center, BethesdaA Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease — Wallace Rheumatic Center, Beverly HillsA Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH) — Arizona Liver Health - Chandler, ChandlerRESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus — University of California Irvine, OrangeA Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) — 89bio Clinical Study Site, BirminghamPhase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension). — Pinnacle Research Group Llc, AnnistonWearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study — Norman Fixel Institute for Neurological Diseases, GainesvilleHarnessing Macrophage Lysosomal Lipid Metabolism in Obesity — University of Missouri School of Medicine, ColumbiaFiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF) — University of Michigan, Ann ArborImproving Coronary Vascular Health in Women — Massachusetts General Hospital, BostonRheumatology Diet Study — UCF Health Clinics, OrlandoBAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus — Nationwide Children's, ColumbusSolriamfetol for the Treatment of Multiple Sclerosis Fatigue — Johns Hopkins University, BaltimoreThe BRIDGE Pain Study — Cincinnati Children's Hospital, CincinnatiHuman Models of Selective Insulin Resistance: Alpelisib, Part I — Columbia University Irving Medical Center, New YorkPRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis — Purushotham & Akther Kotha MD, Inc., La MesaMechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease — Ann & Robert H Lurie Children's Hospital of Chicago, ChicagoEntire-body PET Scans for Multiple Sclerosis — Brain Health Alliance, Ladera RanchA Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis — Arizona Neuroscience Research, LLC, PhoenixInvestigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis — Wayne State University, DetroitA Palliative Care Model Impact on Knowledge and Attitudes — Judith Jaffe Multiple Sclerosis Center, New YorkFibrosis Lessens After Metabolic Surgery — Banner Health Center, PhoenixEASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease — Pinnacle Research Group, LLC, AnnistonEffects of Acute Intermittent Hypoxia on Neuroplasticity in MS — Shirley Ryan AbilityLab, ChicagoCare in Multiple Sclerosis (MS) — University of Alabama at Birmingham, BirminghamA Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis — Stanford University Medical Center, StanfordStaged Kidney Transplantation During Combined Heart/Kidney Transplantation — Cedars-Sinai Medical Center, Los AngelesEffects of Stopping Hydroxychloroquine in Elderly Lupus Disease — University of California, Los Angeles, Los AngelesHome Based Infusions for Ocrelizumab — Amerita, CentennialA Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis — Kessler Foundation, East HanoverStudy to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis — Local Institution - 0114, Loma LindaExercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device — University of Illinois at Chicago, ChicagoTreatment of Participants With Primary or Secondary Progressive Multiple Sclerosis — University of Kansas Medical Center, Kansas CityA Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) — GSK Investigational Site, AnnistonTriage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility — Brooklyn Clinical Research, BrooklynA Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE — Research Site, San FranciscoAIM's Writing for Healing: A Workshop for Individuals Living With Paralysis — 354 School of Health Professions Building, BirminghamA Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH — 89bio Clinical Study Site, BirminghamA Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE) and Sjogren's Disease (SjD) — Life Clinical Trials - Colonial Drive - Margate /ID# 276050, MargateNYSCF Scientific Discovery Biobank — New York Stem Cell Foundation Research Institute, New YorkCentral Vein Sign in Multiple Sclerosis Extension Study — Cedars-Sinai Medical Center, Los AngelesA Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment — Alloy Clinical Research LLC, KissimmeeSotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — Stanford University Medical Center, StanfordA Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) — TG Therapeutics Investigational Trial Site, BirminghamA Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS) — BRIUMVI® Pregnancy Registry Virtual Research Coordination Center, WilmingtonInvestigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS — Kessler Foundation, West OrangeA Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2) — Local Institution - 0011, BirminghamTargeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis — Johns Hopkins University, BaltimoreSPYRAL GEMINI Pilot Study — Stanford Hospital and Clinics, StanfordSkeletal Muscle Aging and Responsiveness in Aged People With MS — Oklahoma Medical Research Foundation, Oklahoma CityExploring the Utility of [18F]3F4AP for Demyelination Imaging — Yale University PET Center, New HavenMotor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis — Georgia State University Biomechanics Lab, AtlantaIntervention to Improve Communication and Medication Adherence in Lupus — Duke University, DurhamA Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH — GSK Investigational Site, ChandlerTransforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus — University of Alabama Birmingham Hospital, BirminghamNASH AMPK Exercise Dosing (AMPED) Trial — Penn State Hershey Medical Center, HersheyFeasibility of The Health Integrated Nutrition and Kidney Wellness Program — UPMC Kidney Clinic - Wexford, PittsburghA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants — Loma Linda University health, Loma LindaREACT-01: Reversing Autoimmunity Through Cell Therapy — Seattle Children's Hospital, SeattleExercise Training for Managing Major Depressive Disorder in Multiple Sclerosis — University of Illinois at Chicago, ChicagoPrepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS? — Jacobs School of Medicine and Biomedical Sciences, Neurology, University at Buffalo, BuffaloHyperpolarized Carbon Metabolic Imaging in Multiple Sclerosis — Byers Hall, San FranciscoAlnuctamab for Refractory SLE (LATTE Study) — Icahn School of Medicine at Mount Sinai, New YorkEndoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease — Brigham and Women's Hospital, BostonThe Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health — University of California, Davis, DavisPharmacy-led Transitions of Care Intervention to Improve Medication Adherence — University of Tennessee Medical Center, KnoxvillePhase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders — MD Anderson Cancer Center, HoustonHOBSCOTCH-MS-Efficacy Trial — Dartmouth-Health Lebanon, LebanonNon-invasive BCI-controlled Assistive Devices — The University of Texas at Austin, AustinMS-ResearchBiomarkerS — Cedars-Sinai Medical Center, Los AngelesA Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis — Alabama Neurology Associates PC, Birmingham

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