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297 studies

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150 studies on the map

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) — Phoenix Children's Hospital, PhoenixA Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease — Uni of Alabama at Birmingham, BirminghamATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders — Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital, PhoenixComparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study — Northern Arizona Healthcare, FlagstaffA Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — Univ of Alabama Birmingham, BirminghamA Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine — Rehabilitation & Neurological Services /ID# 248517, HuntsvilleEfficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects — The Belinga Clinic, Fort SmithA Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine — TrialSphere Corp, Merz Investigational Site #0010513, ChandlerA Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine — Mayo Clinic Hospital, PhoenixA Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine — TrialSphere Corp, Merz Investigational Site #0010513, ChandlerPragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults — University of Alabama at Birmingham, BirminghamA Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years — Rehabilitation and Neurological Services /ID# 270782, HuntsvilleComparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease — Children's of Alabama (MRD-HCT), BirminghamA Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine — Yale-New Haven Children's Hospital - PIN, New HavenA Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine — Xenoscience Inc, PhoenixA Long-term Follow-up Study in Patients Who Received BEAM-101 — University of Alabama at Birmingham, BirminghamThe Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease — University of Alabama at Birmingham- Site Number : 8400003, BirminghamStudy of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine — Central Research Associates /ID# 260161, BirminghamA Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease — University of Alabama at Birmingham, BirminghamResponding With Evidence and Access for Childhood Headaches — University of Alabama at Birmingham Children's of Alabama, BirminghamA Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine — Yale University School of Medicine, New HavenA Study of Eptinezumab in Pediatric Participants With Episodic Migraine — Ki Health Partners LLC DBA New England Institute for Clinical Research, StamfordA Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) — University Of Alabama, BirminghamQudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old — Upsher-Smith Clinical Trial Site #5, BirminghamA Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine — Central Research Associates, LLC (CRA) dba Flourish Research, BirminghamSotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — Stanford University Medical Center, StanfordPeer Support for Adolescents and Emerging Adults With Sickle Cell Pain — University of South Alabama Medical Center, MobileA Phase 2/3 Study in Adult and Adolescent Participants With SCD — Smilow Cancer Hospital, New HavenA Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults — Central Research Associates, BirminghamA Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine — Flourish - Birmingham, BirminghamSafety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis — Univ. of California, San Francisco Health Care, OaklandSPYRAL GEMINI Pilot Study — Stanford Hospital and Clinics, StanfordStudy of EVO756 in Adults With Migraine — CA Medical Clinic for Headache, Los AngelesA Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine — Arkansas Children's Hospital, Little RockLong-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine — Perseverance Research Center, LLC, ScottsdaleRecruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease — University of Alabama, Birmingham (UAB), BirminghamStudy to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17) — Rehabilitation & Neurological Services /ID# 229969, HuntsvilleRandomized Study in Children and Adolescents With Migraine: Acute Treatment — Achieve Clinical Research, LLC d/b/a Accel Research Sites-Neurology and Neurodiagnostic of Alabama, BirminghamAchieving Understanding of the Natural History of Sickle Cell Trait (AUNT) — University of Alabama, BirminghamA Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors — Site 108, ChandlerMMA Embolization for Refractory Chronic Migraine — Barrow Neurological Institute at St. Joseph's Hospital, PhoenixMaridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity — University of Alabama Saint Vincent's Birmingham, BirminghamEASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease — Pinnacle Research Group, LLC, AnnistonRollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study — University Of Alabama, BirminghamA Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) — University of Alabama at Birmingham, BirminghamA Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease — University of Alabama Birmingham, BirminghamEvaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity — Alliance For Multispecialty Research - Daphne, DaphneMinimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease — Children's National Health System, Washington D.C.A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine — Hope Clinical Research, Canoga ParkZinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial — UCSF Benioff Children's Hospital Oakland, OaklandSafety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD) — UAMS Medical Center, Little RockA Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity — Advanced Cardiovascular, LLC, Alexander CityStudy of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease — Site # 8400006, AtlantaSickle Cell Clinical Research and Intervention Program — Children's Hospital of Illinois at OSF-Saint Francis Medical Center, PeoriaGene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease — Children's Hospital Los Angeles, Los AngelesCooperative Assessment of Late Effects for SCD Curative Therapies — Children's National Medical Center, Washington D.C.Supporting Health in Veterans With Heart Failure — VA Clinic - Gainesville, GainesvilleMyeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease — University of California Los Angeles, Los AngelesA Socio-ecological Approach for Improving Self-management in Adolescents With SCD — Nemours Children's Health, WilmingtonRuxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease — Children's Hospital of Colorado, AuroraDelivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease — University of Illinois at Chicago, ChicagoReduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders — Yale School of Medicine, New HavenCombined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD) — Nephrology of North Alabama, DecaturEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease — New York Presbyterian Hospital - Morgan Stanley Children's Hospital, New YorkIntegrative Training Program for Pediatric Sickle Cell Pain — Connecticut Children's Medical Center, HartfordApplying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness — Lurie Children's Hospital, ChicagoSCD Stem Cell Mobilization and Apheresis Using Motixafortide — University of Alabama at Birmingham, BirminghamStudy Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients — Sunwise Clinical Research, Llc, Walnut CreekBE WELL With Migraine: Brain Education and WELLness With Migraine — Cambridge Health Alliance - Center for Mindfulness and Compassion, CambridgeStudy to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks — Neurology and Pain Specialty Center /ID# 278508, Aliso ViejoA Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) — Memorial Sloan Kettering at Basking Ridge (Consent only), Basking RidgeCharacterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System — Hope Center, Washington D.C.Military Health and Nutrition Examination Study — Fort Campbell, Fort CampbellAmerican Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study) — NIDDK-Phoenix Epidemiology and Clinical Research, PhoenixClinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease — Emory University, AtlantaMULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease — UH Seidman Cancer Center Adult SCD Clinic or UH Rainbow Babies and Children's Hospital Sickle Cell Anemia Center, ClevelandMind Body Balance for Pediatric Migraine — University of Colorado/Children's Hospital Colorado, AuroraStudy of the Role of Genetic Modifiers in Hemoglobinopathies — Boston Children's Hospital, BostonReal-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine — University of Miami, Miller School of Medicine, MiamiFeasibility of The Health Integrated Nutrition and Kidney Wellness Program — UPMC Kidney Clinic - Wexford, PittsburghCardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment — Fountains Family Care, ChandlerEffect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia — Magee Women's Hospital, PittsburghFood and Fitness With Medicine (FFWM) — Ohio State Healthy Community Center, ColumbusTezspire Cardiac Events PASS — Healthcare Integrated Research Database (HIRD), WilmingtonA Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors — UConn Health, FarmingtonMechanisms of Semaglutide Therapy in Heart Failure Patients — Greenstone Biosciences, Palo AltoVerifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease — Cincinnati Children's Hospital Medical Center, CincinnatiUnderstanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure — Johns Hopkins Center for Health Equity, BaltimoreSickle Cell Kidney Biorepository — Parkland Memorial Hospital, DallasPharmacy-led Transitions of Care Intervention to Improve Medication Adherence — University of Tennessee Medical Center, KnoxvilleHome Hospital for Suddenly Ill Adults — Brigham and Women's Hospital, BostonMindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF — VA Boston, BostonAI Platform for Fatigue and Depression Detection — Indiana University, IndianapolisArginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease — Children's Healthcare fo Atlanta at Hughes Spalding, AtlantaTransplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease — University of California, Los Angeles, Los AngelesEarly Screening and Treatment of Heart Complication in Sickle Cell Disease — Inova Schar Cancer, FairfaxEffect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease — Methodist Comprehensive Sickle Cell Center, MemphisObservational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepant) or Qulipta (Atogepant) During Pregnancy — Iqvia /Id# 266904, DurhamMind Body Intervention for Chronic Migraine Headaches — Beth Israel Deaconess Medical Center, BostonTriage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility — Brooklyn Clinical Research, BrooklynGENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study — University of Alabama at Birmingham, BirminghamGut Microbiota in Metabolic Surgery — Vanderbilt_University MC, NashvilleLifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients — West Virginia School of Osteopathic Medicine, LewisburgHeart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention — National Institutes of Health Clinical Center, BethesdaWatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time — Arizona State University, TempePRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis — University of Alabama at Birmingham, BirminghamThe Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health — University of California, Davis, DavisMetabolic Effects of Angiotensin-(1-7) — Vanderbilt University Medical Center, NashvilleMitigation of Cardiovascular Disease Risks in Children With Extreme Obesity — University of Kentucky, LexingtonInspire HER: Inspiring the Heart and Emotions for Radical Health — University of Alabama at Birmingham, BirminghamPioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants — Texas Diabetes Institute/UH, San AntonioCommunity Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study — Miami-Dade County Parks, Recreation and Open Spaces Department, MiamiNon-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health. — Clindove Research LLC, BrooklynHIIT Effects on Cardiometabolic Health — Women's Building, SyracuseSympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) — University of Kansas Medical Center, Kansas CityAdapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics — Washington University in St. Louis, St LouisEvaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics — Washington University in St. Louis, St LouisEffects of Whole vs. Nonfat Milk Consumption on Body Composition in Children — New Balance Foundation Obesity Prevention Center, BostonRoutine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) — University of Missouri-Columbia, ColumbiaThe Weight of Cardiovascular Disease — Mayo Clinic in Rochester, RochesterTargeting Breathing Limitations to Improve Functional Outcomes in HFpEF — UT Southwestern Medical Center, DallasEVOC - EVs in Obesity and Cardiometabolic Disease — Massachusetts General Hospital, BostonPrevention of Progression of Prediabetes, Obesity and CV Risk — University of Texas Health Science Center at San Antonio, San AntonioDiabetes and Heart Disease Risk in Blacks — National Institutes of Health Clinical Center, BethesdaNew Heart Imaging Techniques to Evaluate Possible Heart Disease — National Institutes of Health Clinical Center, BethesdaCARBON: UAB Cardiovascular Research Biobank — University of Alabama at Birmingham, BirminghamRole of Adiposomes in Endothelial Dysfunction — University of Illinois at Chicago, ChicagoBlack Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention — The Ohio State University, ColumbusThe Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity — University of Mississippi Medical Center, JacksonImpact of Lean Pork on Endothelial Function in Perimenopause — Pennington Biomedical Research Center, Baton RougeAssociations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status — UVA Student Health and Wellness Building, CharlottesvilleEffects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults — University of Texas Health Science Center at San Antonio, San AntonioFiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF) — University of Michigan, Ann ArborPRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG — Metabolic Research Institute, Inc, West Palm BeachEffect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT — Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center (The Lundquist Institute), TorranceClinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs — Poirot Podiatry, MetairieNT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study — University of Texas Southwestern Medical Center, DallasImproving Coronary Vascular Health in Women — Massachusetts General Hospital, BostonAcute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes — University of Texas Health Science Center at San Antonio, San AntonioImproving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads — University of South Carolina, ColumbiaUsing Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes — UT Southwestern Medical Center, DallasThe Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease — Brigham and Women's Hospital, BostonCare Transitions App for Patients With Multiple Chronic Conditions — Brigham and Women's Hospital, BostonBLOOM: Biological Legacy of Origin in Mother-Infant Dyads — University of Miami/ Holtz Children's Hospital, MiamiFeasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD — University of Michigan, Ann ArborErtugliflozin in Chronic Heart Failure — Yale School of Medicine, New HavenEffect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease — Northwestern University, ChicagoStaged Kidney Transplantation During Combined Heart/Kidney Transplantation — Cedars-Sinai Medical Center, Los Angeles: Vascular Function in Health and Disease — George E Wahlen VA Medical Center, Salt Lake CityStudy of the Effect of Innate on the Inflammatory Response to Endotoxin — NIEHS Clinical Research Unit (CRU), Research Triangle Park

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