TrialPath

467 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

149 studies on the map

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease — Uni of Alabama at Birmingham, BirminghamATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders — Arizona Hemophilia and Thrombosis Treatment Center at Phoenix Children's Hospital, PhoenixA Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia — Univ of Alabama Birmingham, BirminghamStudy of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease — University of Illinois at Chicago, ChicagoSickle Cell, Pain and Mediterranean Diet — University of Illinois Chicago, ChicagoInvestigation of the Genetics of Hematologic Diseases — St. Jude Children's Research Hospital, MemphisStudy to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder — University of Alabama - Huntsville Regional Medical Campus /ID# 267818, HuntsvilleComparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease — Children's of Alabama (MRD-HCT), BirminghamStudy of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder — Clinical Site, BirminghamA Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease — University of Florida, GainesvilleCannabidiol in Sickle Cell Disease — Icahn School of Medicine at Mount Sinai, ManhattanObservational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies — National Institutes of Health Clinical Center, BethesdaA Long-term Follow-up Study in Patients Who Received BEAM-101 — University of Alabama at Birmingham, BirminghamThe Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease — University of Alabama at Birmingham- Site Number : 8400003, BirminghamA Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease — University of Alabama at Birmingham, BirminghamStudy of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder — Clinical Site, ChandlerStudy to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder — Vanda Investigational Site, PhoenixRE104 Safety and Efficacy Study in Generalized Anxiety Disorder — Lighthouse Psychiatry, GilbertA Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) — University Of Alabama, BirminghamPeer Support for Adolescents and Emerging Adults With Sickle Cell Pain — University of South Alabama Medical Center, MobileA Phase 2/3 Study in Adult and Adolescent Participants With SCD — Smilow Cancer Hospital, New HavenExamining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors — Fort Carson, Colorado SpringsSafety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis — Univ. of California, San Francisco Health Care, OaklandRecruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease — University of Alabama, Birmingham (UAB), BirminghamDINO RCT - Treating Anxiety in Children With Autism — Kennedy Krieger Institute, BaltimoreAchieving Understanding of the Natural History of Sickle Cell Trait (AUNT) — University of Alabama, BirminghamNon-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders — Rogers Behavioral Health, OconomowocA Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder — Vistagen Clinical Site, Sherman OaksBaseline Anxiety Trajectories in Pediatric Radiation Therapy Observational Cohort — UT MD Anderson, HoustonA Study of NTX-1472 in Social Anxiety Disorder — SOAR Clinical Study Site, EncinoRollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study — University Of Alabama, BirminghamA Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD) — University of Alabama at Birmingham, BirminghamA Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease — University of Alabama Birmingham, BirminghamMinimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease — Children's National Health System, Washington D.C.Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial — UCSF Benioff Children's Hospital Oakland, OaklandSafety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD) — UAMS Medical Center, Little RockStudy of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease — Site # 8400006, AtlantaTriage Survey for Psychiatry Research Eligibility — Adams Clinical, Boston, BostonSickle Cell Clinical Research and Intervention Program — Children's Hospital of Illinois at OSF-Saint Francis Medical Center, PeoriaGene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease — Children's Hospital Los Angeles, Los AngelesCooperative Assessment of Late Effects for SCD Curative Therapies — Children's National Medical Center, Washington D.C.Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use — 46 Centerra Parkway, Suite 300, Office #333S, LebanonType I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans — Phoenix VA Health Care System, Phoenix, AZ, PhoenixMyeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease — University of California Los Angeles, Los AngelesA Socio-ecological Approach for Improving Self-management in Adolescents With SCD — Nemours Children's Health, WilmingtonRuxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease — Children's Hospital of Colorado, AuroraDelivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease — University of Illinois at Chicago, ChicagoReduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders — Yale School of Medicine, New HavenEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease — New York Presbyterian Hospital - Morgan Stanley Children's Hospital, New YorkIntegrative Training Program for Pediatric Sickle Cell Pain — Connecticut Children's Medical Center, HartfordWellness App for Sleep Disturbance in Hematological Cancer Patients — Arizona State University, PhoenixFamily Spirit Strengths — Johns Hopkins Center for Indigenous Health, ChinleThe Impact of Enhanced Music & Natural Visuals on Emotional Health — Colorado State University, Fort CollinsApplying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness — Lurie Children's Hospital, ChicagoSCD Stem Cell Mobilization and Apheresis Using Motixafortide — University of Alabama at Birmingham, BirminghamStudy of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders — National Institutes of Health Clinical Center, BethesdaA Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) — Memorial Sloan Kettering at Basking Ridge (Consent only), Basking RidgeHeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis — Children's Hospital Los Angeles, Los AngelesRIVER At Home Ketamine Protocols — RIVER Foundation, BigforkProcess-Based Approach Case Series For Anxiety Problems — University of Alabama at Birmingham Dr. Borgogna's lab, BirminghamModulating Exercise Dosage to Improve Concussion Recovery — University of Colorado Denver, AuroraSilverCloud as a School-Based Intervention for Vulnerable Youth — Rutgers University, New BrunswickAnxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's — Anxiety and Behavioral Health Clinic, TallahasseeEffects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial — Lake Forest Hospital, Lake ForestEnhancing Brain And Mental Health Through Breathing Practice — Mayo Clinic Health System-Albert Lea, Albert LeaStepped Care Treatment for Anxiety Resilience — Baylor College of Medicine, HoustonPramipexole to Enhance Social Connections — University of California, San Diego, San DiegoComparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults — University of North Carolina at Chapel Hill, Chapel HillSearch for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness — Acacia Clinics, SunnyvaleBrain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities — Montclair State University, MontclairIntracranial Neurophysiological Signatures of Fear and Anxiety in Humans — University of California Los Angeles, Los AngelesEfficacy Trial of the CALM Intervention — University of Connecticut School of Medicine, West HartfordSleep, Dreaming, and Virtual Reality for Mental Health — Northwestern University, EvanstonLow-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD) — University of California, Los Angeles, Los AngelesCO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy — Boston University, BostonClinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease — Emory University, AtlantaMULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease — UH Seidman Cancer Center Adult SCD Clinic or UH Rainbow Babies and Children's Hospital Sickle Cell Anemia Center, ClevelandThe Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety — The Ohio State University, ColumbusStudy of the Role of Genetic Modifiers in Hemoglobinopathies — Boston Children's Hospital, BostonMental Health in Primary Care — Jessie Trice Community Health Center, MiamiClinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders — SUNY Upstate Medical University, Department of Psychiatry and Behavioural Sciences, SyracuseEnhancing Engagement by Integrating Goals and Concerns That Matter to Patients — Dartmouth Hitchcock Concord Family Medicine, ConcordConfirmatory Efficacy of the Building a Strong Identity and Coping Skills Program — Pennsylvania Psychiatric Institute, HarrisburgEffect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia — Magee Women's Hospital, PittsburghRXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty — UPMC East, MonroevillemHealth Mindfulness With Patients With Serious Illness and Their Caregivers — RWJ Barnabas Outpatient Geriatric Clinics, LivingstonBehavioral Exposure for Introceptive Tolerance RCT — RWJ Cardiac Rehab at East Brunswick, East BrunswickVerifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease — Cincinnati Children's Hospital Medical Center, CincinnatiRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford — Sanford Health, Sioux FallsEscalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease — National Institutes of Health Clinical Center, BethesdaSickle Cell Kidney Biorepository — Parkland Memorial Hospital, DallasPharmacy-led Transitions of Care Intervention to Improve Medication Adherence — University of Tennessee Medical Center, KnoxvilleLakota Family Acceptance Project — Wahwala Iyohlogya/Peaceful Means, Pine RidgeIntegrative Medicine in Pain Management in Sickle Cell Disease, 2.0 — Indiana University School of Medicine, IndianapolisPromoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease — Boston Children's Hospital, BostonPhase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings — Ohana Center for Child and Adolescent Behavioral Health, MontereyPotential Benefits of Parent Child Interaction Therapy (PCIT) — UF Health Child Psychiatry, GainesvilleEnhancing Health in Rural Populations: Music as Therapy — Haven Health Flagstaff, FlagstaffHarlem Strong Mental Health Coalition — CUNY Graduate School of Public Health and Health Policy, New YorkPromoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer — Boston Children's Hospital, BostonVirtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion — Center for Family Planning Research, Magee-Womens Hospital, PittsburghReward Processing and Exposure Therapy for Social Anxiety Disorder — University of California, Los Angeles, Los AngelesArginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease — Children's Healthcare fo Atlanta at Hughes Spalding, AtlantaTransplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease — University of California, Los Angeles, Los AngelesEarly Screening and Treatment of Heart Complication in Sickle Cell Disease — Inova Schar Cancer, FairfaxEffect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease — Methodist Comprehensive Sickle Cell Center, MemphisM-O-M-S on the Bayou: Implementation of an Intervention for Mental Health in Pregnancy — Tulane University, New OrleansProphylactic Transfusion In Pregnant in Women With Sickle Cell Disease — Grady Health System, AtlantaGroup Exposure Workshops for Socially Anxious Undergraduates — Renee Crown Wellness Institute and Department of Psychology & Neuroscience, University of Colorado Boulder, BoulderAllo HSCT for High Risk Hemoglobinopathies — Masonic Cancer Center, MinneapolisLifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients — West Virginia School of Osteopathic Medicine, LewisburgA Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease — University of Illinois at Chicago College of Medicine, ChicagoCommunity Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study — Miami-Dade County Parks, Recreation and Open Spaces Department, MiamiTargeting Social Function in Anxiety and Eating Disorders — UT Southwestern Multispecialty Psychiatry Clinic, DallasBuilding Connections — Disparities Research Unit, Massachusetts General Hospital, BostonFacilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions — Massachusetts General Hospital, BostonCommunity Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study — Miami-Dade County Parks, Recreation and Open Spaces Department, MiamiSickle Cell Disease Biofluid Chip Technology (SCD BioChip) — University Hospitals Case Medical Center, ClevelandThe COMParing App Support Strategies Study — Center for Healthy Minds, MadisonKetamine Treatment Plans for Chronic Conditions — RIVER Telehealth, HelenaUsing TMS to Understand Neural Processes of Social Motivation — Auburn University, AuburnEvaluation of the PACE/PACENET BHL Clinical Program — Department of Psychiatry (Center for Psychotherapy Research), University of Pennsylvania, PhiladelphiaSleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters — California Polytechnic University - San Luis Obispo, San Luis ObispoDigital Intervention for Physical Activity — Kinesiology Building, AuburnAn Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms — CCM Clinical Research Group, MiamiStrengthening Health and Insight in New Educators — University of Alabama, TuscaloosaPET Imaging of Vaso-Occlusive Crisis (VOC) in SCD — UPMC, PittsburghAYA-PeerConnect: A Communication Coaching Intervention for Adolescent/Young Adult Cancer Survivors (AYACS) — Milton S. Hershey Medical Center, HersheyAcceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease — Children's Hospital Los Angeles, Los AngelesIntervention to Enhance Coping and Help-seeking Among Youth in Foster Care — Portland State University, PortlandAlendronate for Osteonecrosis in Adults With Sickle Cell Disease — UC Davis Comprehensive Cancer Center, SacramentoReadiness and Progress in Emotion Regulation Therapy — Teachers College, Columbia University, New YorkDeveloping Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss — The Chicago Lighthouse, ChicagoJust-in-Time Training for Youth Mentors — University of Minnesota, MinneapolisExpressive Writing on Minority Stressors Among Sexual Minority Veterans — VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, BostonPsychiatric Outcomes of Unruptured Intracranial Aneurysms (POUIA) — Montefiore Medical Center, The BronxIndividual Factors of CBT Underlying Success — University of Washington, SeattleNeurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story — Texas Children's Hospital, HoustonVirtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment — Mayo Clinic in Florida, JacksonvillePathways to Perinatal Mental Health Equity — UMass Chan Medical School, ShrewsburyFeasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals — Weill Cornell Medical College, New YorkYouth Emotional and Behavioral Treatment Study — Florida State University, TallahasseeTRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors — The University of Texas M. D. Anderson Cancer Center, HoustonPersonalized Mobile Cognitive Behavioral Therapy Application — Weill Cornell Medical College, New YorkDecoding and Modulating Affective Brain States — University of Pennsylvania, PhiladelphiaNeuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV — Massachusetts General Hospital, BostonA Behavioral mHealth Intervention for People With HIV With Anxiety and Depression — University of Florida, GainesvilleFamily Acceptance Project Online (Pilot RCT) — University of Michigan, Ann ArborCombination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer — MD Anderson Cancer Center, Houston

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