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12 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • Kidney disease

    Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease Patients on Hemodialysis

    Testing amino acid supplements during hemodialysis for fatigue and thinking in end-stage kidney

    📍 The University of Texas Health Science Center at San Antonio · San Antonio, TX · Get directions →

    The study will test and compare the efficacy of a single essential amino acid valine with a combination of essential amino acids (EAA) supplement on fatigue, frailty, and cognitive function in end-stage kidney disease (ESKD) patients undergoing hemodialysis (HD) treatment.

    ✓ Study care freeEarly Phase 1Ages 18–64Learn more →
  • Crohn's / ulcerative colitis (IBD)

    Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

    Studying how statin treatment affects biology in people with primary sclerosing cholangitis

    📍 Stanford University · Stanford, CA · Get directions →

    PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection.

    ✓ Study care freeEarly Phase 1Ages 18–80Learn more →
  • DepressionAnxiety

    Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials

    Testing whether eating more country foods and cultural activities help Inuit adults with depression

    📍 Aqqiumavvik Society · Arviat, Nunavut · Get directions →

    This study is looking at how eating more country foods affects mental health among Inuit men and women in Arviat, NU. The goal is to evaluate if eating more of these foods helps people feel less depressed or anxious, and whether being part of food-gathering and cultural activities also makes a difference.

    ✓ Study care freeEarly Phase 1Ages 18–65Learn more →
  • Crohn's / ulcerative colitis (IBD)

    Effect of Statins on Crohn's Disease

    Testing whether statins can reduce gut narrowing (strictures) in adults with Crohn’s disease

    📍 Stanford University · Stanford, CA · Get directions →

    The goal of this clinical trial is to learn if statins work to prevent strictures in adults with Crohn's disease. The main question it aims to answer is: * Can statins reduce the formation of strictures in participants with stricturing Crohn's disease?

    ✓ Study care freeEarly Phase 1Ages 18–80Learn more →
  • Crohn's / ulcerative colitis (IBD)

    Cranberry and Gut Health in Crohn's Disease

    Testing whether a cranberry supplement helps gut health in people with Crohn’s disease

    📍 UMASS medical center · Worcester, MA · Get directions →

    This study is investigating whether a cranberry-based dietary supplement, rich in polyphenols and fiber, can enhance gut health in individuals with Crohn's disease. People with Crohn's disease often have an imbalance in their gut microbiome (the community of bacteria in the gut).

    ✓ Study care freeEarly Phase 1Ages 18–65Learn more →
  • Kidney disease

    Concomitant Renal and Urinary Bladder Allograft Transplantation

    Testing whether transplanting a new kidney and bladder at the same time is possible for people with

    📍 Mayo Clinic · Rochester, MN · +1 more US site · Get directions →

    The purpose of this study is to establish if concomitant renal and vascularized urinary bladder allograft transplantation is feasible.

    ✓ Study care freeEarly Phase 1Ages 1–60Learn more →
  • Kidney disease

    Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

    Testing whether a trial of SGLT2 inhibitors in youth with chronic kidney disease is feasible

    📍 Ann & Robert H. Lurie Children's Hospital of Chicago · Chicago, IL · Get directions →

    The goal of this study is to learn if a clinical trial of sodium-glucose co-transporter 2 inhibitors (SGLT2i) is possible in youth with chronic kidney disease (CKD). The investigators also plan to explore whether treatment with SGLT2i (Empagliflozin) helps improve risk factors for worsening kidney and heart disease.

    ✓ Study care freeEarly Phase 1Ages 12–25Learn more →
  • Type 2 diabetesKidney disease

    Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

    Testing whether people with type 2 diabetes have early hormone-related kidney risk

    📍 Brigham and Women's Hospital · Boston, MA · Get directions →

    The aim of this protocol is to assess the presence and severity of primary aldosteronism pathophysiology in patients with type 2 diabetes who have, or are at-risk for developing, chronic kidney disease.

    ✓ Study care freeEarly Phase 1Ages 18–80Learn more →
  • Crohn's / ulcerative colitis (IBD)

    68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

    Testing a scan to see early scarring in the small bowel in Crohn’s

    📍 Mayo Clinic · Rochester, MN · Get directions →

    This study is a prospective, case-control study evaluating whether the PET radiotracer 68Ga-FAPI-46 can detect fibrostenosing Crohn's disease in the small bowel. The goal is to determine whether areas of early or developing fibrosis ("pre-stricture" changes) demonstrate uptake of the tracer, which binds to fibroblast activation protein (FAP).

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Anxiety

    Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

    Testing whether taking a mouth medicine works for anxiety in pancreatic cancer

    📍 Cedars-Sinai Medical Center · Los Angeles, CA · Get directions →

    This is a prospective, single center, double blind, randomized, crossover feasibility study of oral ketamine versus placebo for the treatment of anxiety in patients with pancreatic cancer currently receiving or within 12 weeks of receiving cancer targeted therapy. The primary objective is to determine the feasibility of enrolling subjects and treatment adherence.

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Anxiety

    Sleep, Dreaming, and Virtual Reality for Mental Health

    Testing virtual reality and sleep or dreaming practices for anxiety

    📍 Northwestern University · Evanston, IL · +1 more US site · Get directions →

    People spend approximately one-third of their lives asleep, yet sleep is often underused as an opportunity to support psychological well-being. Contemplative traditions, including Tibetan Dream Yoga, have developed practices that use waking imagination and lucid dreaming to explore perception, awareness, and habitual patterns of thinking.

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Anxiety

    Cannabidiol Effects on Learning and Anxiety

    Testing how CBD affects fear learning and anxiety in college students

    📍 University of Connecticut · Storrs, CT · Get directions →

    To examine the extent to which Cannabidiol (CBD) enhances fear conditioning extinction in college undergraduates who show elevated social anxiety. Undergraduates who display elevated social anxiety on standard assessments will be recruited at the University of Connecticut.

    ✓ Study care freeEarly Phase 1Ages 18–50Learn more →