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9 studies
Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Type 2 diabetesHigh cholesterol
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
Testing whether a daily cholesterol medicine, alone or with ezetimibe, works on top of standard
📍 Clinical Research Institute of Arizona · Sun City West, AZ · +19 more US sites · Get directions →
This study will be a placebo-controlled, double-blind, randomized, Phase 3 study to evaluate the efficacy, safety, and tolerability of obicetrapib 10 mg, both as a fixed-dose combination (FDC) with ezetimibe 10 mg and as monotherapy, on top of guideline-recommended lipid-lowering therapy in patients with metabolic syndrome and/or Type 2 Diabetes Mellitus.
- Obesity / overweightType 2 diabetes
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Testing different doses of a medicine for weight loss in people with obesity or overweight and type
📍 Lakeview Clinical Research · Guntersville, AL · +33 more US sites · Get directions →
The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multiple doses compared with placebo for weight management in participants with obesity or overweight and Type 2 diabetes mellitus (T2DM).
- Type 2 diabetes
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Testing different doses of dulaglutide in children with type 2 diabetes
📍 University of Arizona · Tucson, AZ · +39 more US sites · Get directions →
The main purpose of this study is to evaluate additional dosing options for dulaglutide in pediatric participants with Type 2 Diabetes. Participation in this study will last about 8 months.
- Obesity / overweightType 2 diabetes
A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)
Testing a medicine to see its safety and weight-loss effects in adults with obesity or overweight
📍 CenExel Anaheim Clinical Trials · Anaheim, CA · +39 more US sites · Get directions →
The purpose of this clinical study is to learn about the safety and effects of the study medicine to help adults with obesity or overweight and type 2 diabetes lose weight. Being overweight or obese means carrying too much body weight.
- Type 2 diabetes
Exercise and Intranasal Insulin in Type 2 Diabetes
Testing exercise and nasal insulin in people with type 2 diabetes
📍 Robert Wood Johnson University Hospital Clinical Research Center · New Brunswick, NJ · +3 more US sites · Get directions →
About 6.5 million adults in the United States who are 65 or older have dementia. While the exact cause of dementia is not known, it may be due to changes in the brain.
- Type 2 diabetes
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Comparing two early medicine combinations to lower HbA1c in new type 2 diabetes
📍 University Health System Texas Diabetic Institute · San Antonio, TX · +1 more US site · Get directions →
The primary purpose of this study is to evaluate the efficacy, durability, and mechanism of HbA1c reduction produced by the combination of pioglitazone plus tirzepatide compared to metformin plus sitagliptin in patients with recently diagnosed type 2 diabetes mellitus.
- Obesity / overweightType 2 diabetes
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Testing different doses of CagriSema and semaglutide for weight loss in people with obesity, with or
📍 Uni of Alabama at Birmingham · Birmingham, AL · +39 more US sites · Get directions →
This clinical study is testing how the study medicine CagriSema helps people living with obesity, with or without type 2 diabetes (T2D), lose weight. The purpose of the study is to find out how safe and effective CagriSema is for body weight loss in these participants.
- Type 2 diabetes
RCT Glargine vs NPH for Treatment of DM in Pregnancy
Comparing insulin types glargine and NPH for diabetes in pregnancy
📍 Loyola University Medical Center · Maywood, IL · Get directions →
We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy. Currently, many hospitals differ among use of insulin for management of DM in pregnancy, with NPH, glargine and detemir being the most commonly used forms of basal insulin.
- Type 2 diabetesKidney disease
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Testing the safety and effectiveness of injections for people with type 2 diabetes and chronic
📍 Nephrology Consultants · Huntsville, AL · +39 more US sites · Get directions →
The purpose of this study is to assess the safety and efficacy of up to 2 REACT/rilparencel injections in participants with T2DM and CKD.