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This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis. — Washington University in St. Louis, St LouisEvaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain — Shirley Ryan AbilityLab, ChicagoTreatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation — The University of Texas at Dallas, RichardsonEfficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. — Perseverance Research Center, ScottsdaleNARCOMS Registry: A Multiple Sclerosis Registry — UT Southwestern Medical Center, Dallas"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS — University of California, San Francisco, San FranciscoStudy to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab — TG Therapeutics Investigational Trial Site, BirminghamA Single-Center Study to Characterize the Safety and Efficacy of Ublituximab in Older Adults With Relapsing Forms of Multiple Sclerosis (RMS) — Neurology Center of New England P.C., FoxboroughAn Open-label Study of AZD0120 in Adults With Multiple Sclerosis — Research Site, TucsonUblituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis — Northwestern Memorial Hospital, ChicagoEffect of Cooling on Balance Performance in Multiple Sclerosis — Hunter College, Physical Therapy Department, City University of New York, New YorkA Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases — Stanford Neuroscience Health Center, Palo AltoDalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis — MGH Institute of Health Professions, BostonA Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis — Stanford Multiple Sclerosis Center, Palo AltoHome Based Functional Balance Intervention for Multiple Sclerosis — University of Illinois at Chicago, ChicagoNeuromodulating Cortical Regions Involved in Neurogenic Bladder in MS — Houston Methodist Hospital, HoustonA Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity — Alabama Neurology Associates, BirminghamBringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients — University of Michigan, Ann ArborBreathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases — Mayo Clinic in Rochester, RochesterA Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 — University of Colorado, Denver, DenverA Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis — Arizona Neuroscience Research, LLC, PheonixA Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS) — Profound Research, LLC, CarlsbadA Study Evaluating the Presence and Concentration of BRIUMVI™ (Ublituximab) in Breast Milk — PROVIDE Virtual Research Coordination Center, San FranciscoDeciphering Preserved Autonomic Function After Multiple Sclerosis — Mayo Clinic, RochesterIConquerMS™ - a Patient-Powered Research Network for Multiple Sclerosis — Accelerated Cure Project, WalthamPathological Basis of MRI Signal Changes in Multiple Sclerosis — National Institutes of Health Clinical Center, BethesdaEffect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques — National Institutes of Health Clinical Center, BethesdaFall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters — Disability Participation and Quality of Life (DPQOL) Laboratory, UrbanaBest Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) — Stanford Multiple Sclerosis Center, Palo AltoThe SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study — Shepherd Center, AtlantaWearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study — Norman Fixel Institute for Neurological Diseases, GainesvilleSolriamfetol for the Treatment of Multiple Sclerosis Fatigue — Johns Hopkins University, BaltimoreEntire-body PET Scans for Multiple Sclerosis — Brain Health Alliance, Ladera RanchA Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis — Arizona Neuroscience Research, LLC, PhoenixInvestigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis — Wayne State University, DetroitA Palliative Care Model Impact on Knowledge and Attitudes — Judith Jaffe Multiple Sclerosis Center, New YorkEffects of Acute Intermittent Hypoxia on Neuroplasticity in MS — Shirley Ryan AbilityLab, ChicagoCare in Multiple Sclerosis (MS) — University of Alabama at Birmingham, BirminghamA Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis — Stanford University Medical Center, StanfordHome Based Infusions for Ocrelizumab — Amerita, CentennialA Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis — Kessler Foundation, East HanoverStudy to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis — Local Institution - 0114, Loma LindaExercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device — University of Illinois at Chicago, ChicagoTreatment of Participants With Primary or Secondary Progressive Multiple Sclerosis — University of Kansas Medical Center, Kansas CityAIM's Writing for Healing: A Workshop for Individuals Living With Paralysis — 354 School of Health Professions Building, BirminghamNYSCF Scientific Discovery Biobank — New York Stem Cell Foundation Research Institute, New YorkCentral Vein Sign in Multiple Sclerosis Extension Study — Cedars-Sinai Medical Center, Los AngelesA Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) — TG Therapeutics Investigational Trial Site, BirminghamA Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS) — BRIUMVI® Pregnancy Registry Virtual Research Coordination Center, WilmingtonInvestigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS — Kessler Foundation, West OrangeA Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2) — Local Institution - 0011, BirminghamTargeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis — Johns Hopkins University, BaltimoreSkeletal Muscle Aging and Responsiveness in Aged People With MS — Oklahoma Medical Research Foundation, Oklahoma CityExploring the Utility of [18F]3F4AP for Demyelination Imaging — Yale University PET Center, New HavenMotor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis — Georgia State University Biomechanics Lab, AtlantaExercise Training for Managing Major Depressive Disorder in Multiple Sclerosis — University of Illinois at Chicago, ChicagoPrepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS? — Jacobs School of Medicine and Biomedical Sciences, Neurology, University at Buffalo, BuffaloHyperpolarized Carbon Metabolic Imaging in Multiple Sclerosis — Byers Hall, San FranciscoHOBSCOTCH-MS-Efficacy Trial — Dartmouth-Health Lebanon, LebanonNon-invasive BCI-controlled Assistive Devices — The University of Texas at Austin, AustinMS-ResearchBiomarkerS — Cedars-Sinai Medical Center, Los AngelesA Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis — Alabama Neurology Associates PC, BirminghamDevelopment of Camera Based Gait Quality Measure for Persons With Multiple Sclerosis — Shirley Ryan AbilityLab, ChicagoIncreasing Physical Activity for Adults With Multiple Sclerosis (MS) — UW Medicine, SeattleProspective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod — University of Colorado Anschutz Medical Campus, AuroraIntermittent Hypoxia in Persons With Multiple Sclerosis — Shirley Ryan AbilityLab, ChicagoA Study of the MIND Diet for Persons With Multiple Sclerosis — Mount Sinai Hospital, New YorkStudy of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis — Johns Hopkins University, BaltimoreConfirmatory Trial for Alleviating Fatigue in Multiple Sclerosis — Washington VA Medical Center, Washington D.C.Smoldering Inflammation in MS — Barnes Jewish Center for Clinical Imaging Research, St LouisMetformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS) — UBMD Neurolgy, BuffaloPregnancy Exposure Registry for Vumerity (Diroximel Fumarate) — University of Colorado Anschutz Medical Campus, AuroraGlucose Consumption in MS Using [F-18]FDG-PET — Brigham & Women's Hospital, BostonIntestinal Immunity in Neurologic Disease — Yale MS Clinic, North HavenSilodosin for Urinary Symptoms in Female Patients With Multiple Sclerosis — Atlantic Health, MorristownObe-cel in Refractory Progressive Forms of Multiple Sclerosis — Stanford University, Redwood CityTesting the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community — Kessler Foundation, East HanoverPregnancy Registry, Infants, Serum/Milk Analysis (PRISMA) — University of California-San Francisco, San FranciscoEffects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple Sclerosis — University of St. Augustine for Health Sciences, Saint AugustineFunctional Balance Intervention in Multiple Sclerosis — University of Illinois at Chicago, ChicagoAssessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy — Sandler Neurosciences Building, Neurological Clinical Research Unit, San FranciscoDry Needling in Multiple Sclerosis — Mobility and Falls Lab, Kansas CityNasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis — Brigham and Women's Hospital, BostonExploration of Novel Imaging Biomarkers on OCT for Ublituximab Treatment Response in Multiple Sclerosis — University of Maryland, Baltimore, BaltimoreNon-invasive Electrical Spinal Cord Stimulation To Restore Upper Extremity Function in Multiple Sclerosis — University of Washington, SeattleVascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension — UMass Boston, BostonEfficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis — University of Kansas Medical Center, Kansas CityComparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection — University of Kansas Medical Center- Sleep, Health and Wellness Laboratory, Kansas CityMultiple Sclerosis Implementation Network (Registry) — Multiple Sclerosis Association of America, Cherry HillRemote Evaluation of MIND Diet — University of Illinois Urbana-Champaign, UrbanaIncremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis — Emory Univeristy, AtlantaEccentric Exercise and Fatigue in Multiple Sclerosis — Hunter College, Physical Therapy Department, City University of New York, New YorkTask Specific Training for Advanced Multiple Sclerosis — Hunter College, Physical Therapy Department, City University of New York, New YorkEffect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS) — Keck School of Medicine of the University of Southern California, Los AngelesDevelopment of Pain Management JITAI Content in Multiple Sclerosis and Spinal Cord Injury — University of Michigan, Ann ArborPeople With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists — Northwestern Memorial Hospital, ChicagoA Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis — Profound Research, LLC, CarlsbadA Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years — Boston Clinical Trials Inc - Internal Medicine, BostonKesimpta (Ofatumumab) Pregnancy Registry — University of California San Diego OTIS, La JollaProspective Investigation of Multiple Sclerosis in the Three Rivers Region — University of Pittsburgh, PittsburghAssessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714. — University of Alabama at Birmingham Medical Center, BirminghamA Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease — Knowledge Research Center, OrangeLongitudinal Cognitive Assessment by BoCA — Andrey Vyshedskiy, MiamiEffects of Ublituximab on Motor Functions in Multiple Sclerosis — Georgia State University, AtlantaAutoimmune Intervention Mastery Course Study — Univeristy of Iowa, Iowa CityOcrelizumab Discontinuation in Relapsing Multiple Sclerosis — Yale School of Medicine, New HavenSafety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers — UCSF, San FranciscoBlood Flow Restriction And Veterans With MS — Rocky Mountain Regional VA Medical Center, Aurora, CO, AuroraDry Needling in Multiple Sclerosis — University of South Florida, TampaNon-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis — North Central Neurology Associates- Site Number : 8401100, CullmanIdentifying and Characterizing Preclinical MS — Yale University, North HavenCentral Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy — National Institutes of Health Clinical Center, BethesdaStudy to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple Sclerosis — Minneapolis Clinic of Neurology, Golden ValleyImpact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis — Cleveland State University, ClevelandLongitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders — Mount Sinai Hospital, New YorkMagnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS) — National Institutes of Health Clinical Center, BethesdaComprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System — National Institutes of Health Clinical Center, BethesdaGenes and Environment in Multiple Sclerosis — National Institute of Neurological Disorders and Stroke, BethesdaComplementary and Alternative Care in Multiple Sclerosis — Bastyr University Clinical Research Center, KenmorePET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases — Brigham MS Center, 60 Fenwood Road, BostonAssessment of Synaptic Density in MS — Brigham and Women's Hospital, BostonTargeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS) — National Institutes of Health Clinical Center, BethesdaClinical Applications of Advanced Ophthalmic Imaging — Bascom Palmer Eye Institute, MiamiMolecular Imaging of NET Using [C-11]MRB-PET in MS — Brigham MS Center, 60 Fenwood Road, BostonRetinal Imaging in Neurodegenerative Disease — Duke University Medical Center, DurhamECoG BMI for Motor and Speech Control — University of California San Francisco, San FranciscoTesting an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO — University of Alabama at Birmingham Cancer Center, BirminghamUser-friendliness of a Portable Driving Simulator — Abiodun Akinwuntan, Kansas CityPrevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis — Beth Israel Deaconess Medical Center, BostonInvestigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects — Massachusetts General Hospital, BostonUnhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research — Brain Inflammation Collaborative, DelafieldPost-Authorization Safety Study for Assessment of Pregnancy Outcomes in Patients Treated With Mayzent — Novartis Investigative Site, La JollaAn Individualized-health eLibrary App for People With Multiple Sclerosis — University of Illinois Urbana-Champaign, ChampaignA Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring — Evidera INC., BethesdaMechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype — University of Michigan, Ann ArborReducing Fatigue in People With Multiple Sclerosis by Treatment With TENS — University of Colorado, BoulderVancomycin Study in Multiple Sclerosis (MS) — Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Sinai, New YorkNomad P-KAFO Study — Shirley Ryan AbilityLab, Chicago

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