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6 studies
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- Migraine / chronic headache
Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US
Testing rimegepant taken before a known trigger to prevent predictable migraine
📍 MedStar Health: Neurology at McLean · McLean, VA · Get directions →
Single-center, open label, prospective study conducted at Medstar Georgetown Headache Center. Men and woman ≥ 18 years old that are diagnosed with migraine with or without aura for at least 1 year, who report a reliable migraine trigger.
- Migraine / chronic headache
A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache
Comparing a migraine medicine tablet that dissolves in the mouth to another for adults with migraine
📍 Maimonides Medical Center · Brooklyn, NY · Get directions →
Rimegepant (Nurtec) is an orally administered small molecule CGRP receptor antagonist with efficacy in the acute treatment of migraine. Rizatriptan benzoate (MAXALT), is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist.
- Migraine / chronic headache
A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine
Testing how safe it is to take an extra dose of rimegepant for migraine
📍 Hope Clinical Research · Canoga Park, CA · +6 more US sites · Get directions →
Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack. International Headache Society (IHS) global practice recommendations for the Acute Treatment of Migraine suggest a second dose of the same medication within the recommended dose limit in people with headache relapse after successful initial treatment of a migraine attack.
- Migraine / chronic headache
Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications
Testing whether a migraine attack medicine works and is tolerated in people using preventive CGRP
📍 Mayo Clinic in Arizona · Phoenix, AZ · Get directions →
Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.
- Migraine / chronic headache
Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old
Testing Qudexy XR to prevent migraine in children ages 6 to 11
📍 Upsher-Smith Clinical Trial Site #5 · Birmingham, AL · +14 more US sites · Get directions →
A Phase 4 study to evaluate Qudexy XR for the prevention of migraine in children 6 to 11 years of age.
- Migraine / chronic headache
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
Comparing three medicines to prevent migraine headaches
📍 Northern Arizona Healthcare · Flagstaff, AZ · +34 more US sites · Get directions →
This goal of this study is to compare three medications used for migraine preventive treatment. This study will compare atogepant, a newer migraine preventive medication, with two older preventive medications, topiramate and propranolol.