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Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Migraine / chronic headache
📍 Rehabilitation & Neurological Services /ID# 248517 · Huntsville, AL · +39 more US sites · Get directions →
A migraine is a moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms.
- Migraine / chronic headache
📍 The Belinga Clinic · Fort Smith, AR · +39 more US sites · Get directions →
The purpose of this study is to compare the efficacy and safety of rimegepant to placebo as a preventative treatment for migraine in children and adolescents ≥ 6 to \<18 years with episodic migraine.
- Migraine / chronic headache
📍 TrialSphere Corp, Merz Investigational Site #0010513 · Chandler, AZ · +39 more US sites · Get directions →
In this clinical trial, participants with episodic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections.
- Migraine / chronic headache
📍 Mayo Clinic Hospital · Phoenix, AZ · +31 more US sites · Get directions →
The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in women who experience menstrual migraine attacks.
- Migraine / chronic headache
📍 TrialSphere Corp, Merz Investigational Site #0010513 · Chandler, AZ · +39 more US sites · Get directions →
In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections.
- Migraine / chronic headache
📍 Rehabilitation and Neurological Services /ID# 270782 · Huntsville, AL · +30 more US sites · Get directions →
Migraine is a disease that most often causes moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms.
- Migraine / chronic headache
📍 Yale-New Haven Children's Hospital - PIN · New Haven, CT · +21 more US sites · Get directions →
To find out if eptinezumab is better than placebo (normal saline solution) in lowering the number of days with migraine in young people ages 12 to 17 with chronic migraine.
- Migraine / chronic headache
📍 Xenoscience Inc · Phoenix, AZ · +26 more US sites · Get directions →
The purpose of this study is to learn about the effect of a study medicine called rimegepant in adolescents who have frequent migraine attacks. Rimegepant is a tablet that dissolves when you put it on or under your tongue.
- Migraine / chronic headache
📍 Central Research Associates /ID# 260161 · Birmingham, AL · +39 more US sites · Get directions →
A migraine is a moderate to severe headache typically on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms.
- Migraine / chronic headache
📍 Yale University School of Medicine · New Haven, CT · +19 more US sites · Get directions →
The main goal of the study is to assess the long-term safety of eptinezumab on children and adolescents ages 6 to 17 with chronic or episodic migraine.
- Migraine / chronic headache
📍 Ki Health Partners LLC DBA New England Institute for Clinical Research · Stamford, CT · +14 more US sites · Get directions →
The main goal of this trial is to learn whether eptinezumab helps reduce the number of days with episodic migraine in pediatric participants.
- Migraine / chronic headache
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
📍 Central Research Associates, LLC (CRA) dba Flourish Research · Birmingham, AL · +39 more US sites · Get directions →
This is a double-blind, randomized, multicenter, outpatient evaluation of the efficacy, safety, and tolerability of elismetrep, as compared with placebo, in the acute treatment of migraine.
- Migraine / chronic headache
📍 Central Research Associates · Birmingham, AL · +39 more US sites · Get directions →
A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head. It is often accompanied by feeling or being sick and a sensitivity to bright lights and sound.
- Migraine / chronic headache
📍 Flourish - Birmingham · Birmingham, AL · +15 more US sites · Get directions →
The purpose of this Phase 2 study is to evaluate the safety and efficacy of SC MEDI0618 compared to placebo in participants with episodic migraine.
- Migraine / chronic headache
📍 CA Medical Clinic for Headache · Los Angeles, CA · +12 more US sites · Get directions →
This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.
- Migraine / chronic headache
📍 Perseverance Research Center, LLC · Scottsdale, AZ · +38 more US sites · Get directions →
The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of migraine in children and adolescents (≥ 6 to \< 18 years of age).
- Migraine / chronic headache
📍 Rehabilitation & Neurological Services /ID# 229969 · Huntsville, AL · +39 more US sites · Get directions →
Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Migraine is extremely common and disabling in children.
- Migraine / chronic headache
📍 Achieve Clinical Research, LLC d/b/a Accel Research Sites-Neurology and Neurodiagnostic of Alabama · Birmingham, AL · +39 more US sites · Get directions →
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
- Migraine / chronic headache
📍 CHAMP Research (Calgary Headache Assessment & Management Program) · Calgary, Alberta · Get directions →
This study will evaluate the efficacy and safety of cannabis for the treatment of chronic migraine headaches. Study subjects will be randomized to one of three groups: lower dose CBD, higher dose CBD or placebo.
- Migraine / chronic headache
📍 Sunwise Clinical Research, Llc · Walnut Creek, CA · +2 more US sites · Get directions →
This study is testing an investigational inhaled migraine medication to see how well it works, how safe it is, and how well people tolerate it. Adults with migraine will receive both the study medication (ASY202) and a placebo (inactive treatment) at different times during the study.
- Migraine / chronic headache
📍 VA Connecticut Healthcare System · West Haven, CT · Get directions →
In previous clinical trial work, the investigators observed lasting reductions in headache burden after limited dosing of psilocybin. This purpose of this study is to examine potential sources for this observed effect.
- Migraine / chronic headache
📍 Mayo Clinic in Rochester · Rochester, MN · Get directions →
The purpose of this study is to see how well blocking two to ten of the scalp nerves (that give feeling to the scalp and are painful during migraine headaches) with bupivacaine anesthetic (numbing medication) and low dose methylprednisolone (cortisone-like medicine or steroid) work for treating and preventing migraines. Our hypothesis is that the pain of most episodic migraine headaches can be eliminated and prevented for months by blocking the nerves that give pain sensation during a migraine.
- Migraine / chronic headache
📍 University Medical Center of El Paso · El Paso, TX · Get directions →
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
- Migraine / chronic headache
📍 Advocate Christ Medical Center Emergency Department · Oak Lawn, IL · Get directions →
The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.
- Migraine / chronic headache
📍 Neuroscience Institute at Great Neck · Great Neck, NY · Get directions →
The main purpose of this study is to evaluate the effectiveness of a new treatment in improving chronic migraine symptoms. This treatment involves a targeted lidocaine infusion into blood vessels in the skull to numb pain receptors, potentially leading to improvements in chronic migraine intensity, frequency, and duration.
- Migraine / chronic headache
📍 Naval Medical Center Camp Lejeune · Jacksonville, NC · Get directions →
Chronic migraine (CM) is a disabling disorder that sidelines active duty personnel and diminishes their quality of life. It affects 1.3% to 2.4% of the general population.
- Migraine / chronic headache
📍 Peter H Hwang · Stanford, CA · Get directions →
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain.
- Migraine / chronic headache
📍 University of British Columbia · Vancouver, British Columbia · Get directions →
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.