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11 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • Crohn's / ulcerative colitis (IBD)

    Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

    Studying how statin treatment affects biology in people with primary sclerosing cholangitis

    📍 Stanford University · Stanford, CA · Get directions →

    PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection.

    ✓ Study care freeEarly Phase 1Ages 18–80Learn more →
  • DepressionAnxiety

    Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials

    Testing whether eating more country foods and cultural activities help Inuit adults with depression

    📍 Aqqiumavvik Society · Arviat, Nunavut · Get directions →

    This study is looking at how eating more country foods affects mental health among Inuit men and women in Arviat, NU. The goal is to evaluate if eating more of these foods helps people feel less depressed or anxious, and whether being part of food-gathering and cultural activities also makes a difference.

    ✓ Study care freeEarly Phase 1Ages 18–65Learn more →
  • Crohn's / ulcerative colitis (IBD)

    Effect of Statins on Crohn's Disease

    Testing whether statins can reduce gut narrowing (strictures) in adults with Crohn’s disease

    📍 Stanford University · Stanford, CA · Get directions →

    The goal of this clinical trial is to learn if statins work to prevent strictures in adults with Crohn's disease. The main question it aims to answer is: * Can statins reduce the formation of strictures in participants with stricturing Crohn's disease?

    ✓ Study care freeEarly Phase 1Ages 18–80Learn more →
  • Crohn's / ulcerative colitis (IBD)

    Cranberry and Gut Health in Crohn's Disease

    Testing whether a cranberry supplement helps gut health in people with Crohn’s disease

    📍 UMASS medical center · Worcester, MA · Get directions →

    This study is investigating whether a cranberry-based dietary supplement, rich in polyphenols and fiber, can enhance gut health in individuals with Crohn's disease. People with Crohn's disease often have an imbalance in their gut microbiome (the community of bacteria in the gut).

    ✓ Study care freeEarly Phase 1Ages 18–65Learn more →
  • Obesity / overweightHigh blood pressure

    Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension

    Testing whether angiotensin-(1-7) affects heart health in people with obesity and high blood

    📍 Penn State Milton S. Hershey Medical Center · Hershey, PA · Get directions →

    Obesity is a global health concern that is associated with high blood pressure and an increased risk for developing cardiovascular disease. The purpose of this study is to find out if the investigational drug angiotensin-(1-7) can improve cardiovascular health in people with obesity and high blood pressure.

    ✓ Study care freeEarly Phase 1Ages 18–65Learn more →
  • Lupus (SLE)

    Safety and Efficacy of ONT01 in Lupus

    Studying whether ONT01 is safe and tolerated in people with lupus

    📍 Hospital for Special Surgery · New York, NY · Get directions →

    ONT01 is a drug that is being studied for the treatment of Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE) and is not approved by the FDA. The purpose of this study is to better determine whether ONT01 is safe and tolerated by people with lupus nephritis or SLE.

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Crohn's / ulcerative colitis (IBD)

    68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

    Testing a scan to see early scarring in the small bowel in Crohn’s

    📍 Mayo Clinic · Rochester, MN · Get directions →

    This study is a prospective, case-control study evaluating whether the PET radiotracer 68Ga-FAPI-46 can detect fibrostenosing Crohn's disease in the small bowel. The goal is to determine whether areas of early or developing fibrosis ("pre-stricture" changes) demonstrate uptake of the tracer, which binds to fibroblast activation protein (FAP).

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Anxiety

    Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

    Testing whether taking a mouth medicine works for anxiety in pancreatic cancer

    📍 Cedars-Sinai Medical Center · Los Angeles, CA · Get directions →

    This is a prospective, single center, double blind, randomized, crossover feasibility study of oral ketamine versus placebo for the treatment of anxiety in patients with pancreatic cancer currently receiving or within 12 weeks of receiving cancer targeted therapy. The primary objective is to determine the feasibility of enrolling subjects and treatment adherence.

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Anxiety

    Sleep, Dreaming, and Virtual Reality for Mental Health

    Testing virtual reality and sleep or dreaming practices for anxiety

    📍 Northwestern University · Evanston, IL · +1 more US site · Get directions →

    People spend approximately one-third of their lives asleep, yet sleep is often underused as an opportunity to support psychological well-being. Contemplative traditions, including Tibetan Dream Yoga, have developed practices that use waking imagination and lucid dreaming to explore perception, awareness, and habitual patterns of thinking.

    ✓ Study care freeEarly Phase 1Ages 18+Learn more →
  • Obesity / overweightHigh blood pressure

    Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

    Studying how the nervous system controls blood pressure in obesity and high blood pressure

    📍 University of Texas Southwestern Medical Center · Dallas, TX · Get directions →

    The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function.

    ✓ Study care freeEarly Phase 1Ages 18–55Learn more →
  • Anxiety

    Cannabidiol Effects on Learning and Anxiety

    Testing how CBD affects fear learning and anxiety in college students

    📍 University of Connecticut · Storrs, CT · Get directions →

    To examine the extent to which Cannabidiol (CBD) enhances fear conditioning extinction in college undergraduates who show elevated social anxiety. Undergraduates who display elevated social anxiety on standard assessments will be recruited at the University of Connecticut.

    ✓ Study care freeEarly Phase 1Ages 18–50Learn more →