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23 studies
Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Eczema / atopic dermatitis
Molecular Signatures of Cutaneous Dupilumab Response
Studying how dupilumab affects immune cells in eczema skin
📍 University of California, San Francisco · San Francisco, CA · Get directions →
This study examines the effect of IL4RA blockade with dupilumab on the immune cells of atopic dermatitis skin lesions.
- Eczema / atopic dermatitis
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
Testing whether an experimental medicine is safe and works for eczema
📍 Northridge Clinical Trials · Northridge, CA · +3 more US sites · Get directions →
The purpose of this study is to learn if the study medicine (PF-08049820) is safe and effective for the treatment of atopic dermatitis (AD), also known as eczema, or atopic eczema. People with this condition may have severe itching and rashes on the skin.
- Eczema / atopic dermatitis
Cardamom and Topical Roseomonas in Atopic Dermatitis
Testing cardamom and a skin-applied germ to treat eczema
📍 National Institutes of Health Clinical Center · Bethesda, MD · Get directions →
Background: Atopic dermatitis (AD), also called eczema, is a chronic skin condition. AD can make skin dry and itchy, and sometimes it can lead to serious health problems, such as asthma, food allergies, eye infections, and sleep problems.
- Eczema / atopic dermatitis
A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis
Testing the long-term safety and effects of a drug in people with eczema
📍 Investigational Site · Fountain Valley, CA · +21 more US sites · Get directions →
This is a multicenter, double-blind, Long-Term Extension (LTE) study to evaluate the long-term safety and efficacy of APG777 in patients with moderate-to-severe AD who have completed treatment in an APG777 Parent Study (NCT06395948). The LTE study will consist of 3 periods: 1) Screening Visit will coincide with the last visit of the Maintenance Period in the Parent Study 2) Extended Treatment Period 3) Post-treatment Follow-up Period.
- Eczema / atopic dermatitis
Dupilumab De-escalation in Pediatric Atopic Dermatitis
Testing whether stopping or lowering eczema treatment works for kids
📍 Johns Hopkins Univerisity · Baltimore, MD · Get directions →
This is a pilot investigator-blinded, randomized clinical trial to assess the feasibility of dupilumab treatment discontinuation or dose-reduction in children aged 1-17 years who have achieved sustained atopic dermatitis (AD) control on dupilumab.
- Eczema / atopic dermatitis
A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis
Testing a medicine for moderate to severe eczema, compared with a placebo
📍 Mountain West Derm - Blackhart PLLC dba Skin Cancer and Dermatology Institute · Phoenix, AZ · +39 more US sites · Get directions →
This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.
- Eczema / atopic dermatitis
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Testing different doses of a medicine versus placebo for eczema
📍 Inmagene Site 1 · Lancaster, CA · +14 more US sites · Get directions →
The purpose of this study is to evaluate the efficacy and safety of different dose regimens of IMG-007, compared to placebo.
- Eczema / atopic dermatitis
Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD
Testing how different doses of soquelitinib work for moderate to severe atopic dermatitis
📍 Corvus Clinical Trials · South San Francisco, CA · Get directions →
The main purpose of this study is to see how well different doses of soquelitinib work in participants with atopic dermatitis (AD) as compared to a placebo (pill with no medicine in it). To check this, the study doctors will examine participants' skin regularly to track how their AD changes during the study.
- Eczema / atopic dermatitis
Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome
Testing a daily medicine for eczema and hair loss in people with Down syndrome
📍 Icahn School of Medicine at Mount Sinai · New York, NY · Get directions →
This is a single-center, open-label, basket phase 2b trial that will enroll Down Syndrome (DS) participants with at least one inflammatory skin condition (Atopic Dermatitis (AD) and/or Alopecia Areata (AA)). Patients will receive Abrocitinib 100 mg daily for 12 weeks.
- Eczema / atopic dermatitis
A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis
Checking the long-term safety and effects of an eczema medicine in people who previously studied it
📍 Hamilton Research, LLC · Alpharetta, GA · +2 more US sites · Get directions →
This study will assess long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with Atopic Dermatitis (AD) who participated in previous afimkibart clinical trials.
- Eczema / atopic dermatitis
Lebrikizumab in Moderate-to-severe Atopic Dermatitis
Testing a medicine called lebrikizumab for long-term improvement in eczema
📍 Physioseq USA - CA · Folsom, CA · +1 more US site · Get directions →
This research is studying a drug already approved for the treatment of atopic dermatitis (AD). This research collects health-related information and blood and skin samples to understand if the study drug, lebrikizumab, leads to long-term improvement in AD skin.
- Eczema / atopic dermatitis
Ethnic Differences in Mechanisms of Action of Dupilumab
Studying how a common eczema treatment works differently by race
📍 University of Michigan · Ann Arbor, MI · Get directions →
Previous research has shown that Asian and African Americans are more likely to develop atopic dermatitis (AD) than their Caucasian counterparts. However, limited information is known about AD in Asian and African American populations because most molecular studies have focused on Caucasians with AD.
- Eczema / atopic dermatitis
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
Testing how camoteskimab works in adults with moderate to severe eczema
📍 AllerVie Clinical Research · Birmingham, AL · +32 more US sites · Get directions →
This is a phase 2b, multicenter, randomized, double-blind, placebo-controlled study.
- Eczema / atopic dermatitis
A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab
Testing how a skin injection changes molecules in adults with eczema
📍 Physioseq, LLC /ID# 267266 · Sacramento, CA · +1 more US site · Get directions →
Hidradenitis suppurativa (HS) and atopic dermatitis (AD) are chronic inflammatory skin diseases that lead to the development of skin lesions and symptoms such as pain and discomfort. The purpose of this study is to assess molecular changes in adult participants with moderate to severe HS or with moderate to severe AD.
- Eczema / atopic dermatitis
Evaluate Efficacy and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis
Testing repeat under-the-skin doses of FB825 for adult eczema
📍 First OC Dermatology · Fountain Valley, CA · +5 more US sites · Get directions →
This is a randomized, placebo-controlled and double-blind study to evaluate the efficacy, pharmacokinetics, and Safety of repeat subcutaneous doses of FB825 in adults with moderate-to-severe atopic dermatitis.
- Eczema / atopic dermatitis
A Double-Blind, Randomized, Vehicle-Controlled Phase 2 Study to Assess the Efficacy and Safety of GX-03 in Adult Subjects With Moderate to Severe Atopic Dermatitis (Eczema)
Testing a topical ointment to see if it helps adult eczema and is safe
📍 ALS Global · Irving, TX · Get directions →
This is a Phase 2, randomized, double-blind, vehicle-controlled clinical study evaluating the efficacy and safety of GX-03 topical ointment in adult subjects with moderate to severe atopic dermatitis (eczema). The study plans to enroll up to 120 eligible patients with a target of at least 100 completing the study and an ability to expand enrollment up to 200 subjects based on a pre-specified interim assessment conducted by an Independent Data Monitoring Committee (IDMC).
- Eczema / atopic dermatitis
A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis
Testing different doses of galvokimig for adults with eczema
📍 Atd002 52021 · Oceanside, CA · +19 more US sites · Get directions →
The purpose of the study is to evaluate the dose-response relationship of galvokimig compared with placebo in study participants with moderate-to-severe atopic dermatitis (AtD).
- Eczema / atopic dermatitis
Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
Testing a daily medicine for eczema severity in adults over 12 weeks
📍 Enveda Investigative Site · Birmingham, AL · +22 more US sites · Get directions →
The goal of this clinical trial is to learn about the safety and effectiveness of ENV-294 in adults with moderate to severe atopic dermatitis. The main questions it will answer are: * Is there an impact on the severity and area of atopic dermatitis when participants take ENV-294 * What medical problems do participants have when taking ENV-294 Participants will: * Take drug ENV-294 or a placebo once every day for 12 weeks * Visit the clinic every 2 to 4 weeks for checkups and tests * Keep a diary of their symptoms and when they took their study drug * Return to the clinic for the final study visit at approximately week 16
- Eczema / atopic dermatitis
A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
Testing two medicines for safety and effects in people with eczema
📍 Allervie Clinical Research · Birmingham, AL · +39 more US sites · Get directions →
The purpose of this study is to learn about the safety and effects of 2 study medicines (PF-07275315 and PF-07264660) for the treatment of atopic dermatitis (AD). AD is a long- lasting itchy red rash, caused by a skin reaction.
- Eczema / atopic dermatitis
Effects of Treatments on Atopic Dermatitis
Testing treatments for eczema (atopic dermatitis)
📍 National Institutes of Health Clinical Center · Bethesda, MD · Get directions →
Background: \- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S.
- Eczema / atopic dermatitis
Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
Testing how dupilumab affects sleep, itching, and body clock in children with moderate to severe
📍 Lurie Children's Hospital/Northwestern University · Chicago, IL · Get directions →
Single center, prospective, Open label study of sleep, pruritus and circadian function pre/post 12-weeks of dupilumab treatment in children 6-17 years old
- Eczema / atopic dermatitis
Dupixent and Narrowband UVB for Atopic Dermatitis
Testing dupilumab plus narrowband UVB light for eczema over 24 weeks
📍 Eczema Treatment Center of New Jersey · East Windsor, NJ · Get directions →
24 weeks open-label study with dupilumab and narrowband UVB phototherapy three times weekly for 12 weeks followed by 12 weeks of dupilumab monotherapy.
- Eczema / atopic dermatitis
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Testing medicines for safety and how well they work for moderate to severe eczema
📍 Novartis Investigative Site · Birmingham, AL · +21 more US sites · Get directions →
This trial is designed to evaluate multiple compounds in participants with moderate to severe atopic dermatitis (AD).