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3 studies
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- High cholesterol
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
Testing how safe and well weekly injections of alirocumab work for high cholesterol in adults
📍 Anaheim Clinical Trials · Anaheim, CA · +29 more US sites · Get directions →
This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels).
- High cholesterolLupus (SLE)
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
Testing certolizumab added to usual treatment to improve pregnancy in lupus and antiphospholipid
📍 Hospital for Special Surgery · New York, NY · +1 more US site · Get directions →
This treatment trial evaluates the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose aspirin) in pregnant women with antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this regimen will improve pregnancy outcomes. All enrolled patients will receive certolizumab, and pregnancy outcomes will be compared to those of women with APS and repeatedly positive tests for LAC enrolled in a previous study by the investigators.
- High cholesterol
Liver Adiposity Effects on Pediatric Statin
Measuring how liver fat affects how children take and respond to statin
📍 Children's Mercy Hospital · Kansas City, MO · Get directions →
Single center, open-label, prospective investigation to quantify the effects hepatocellular fat has on hepatic statin transport and response in children and adolescents in obese and non-obese children and adolescents 8-21 years of age with normal, wild-type SLCO1B1 c.521TT genotype that are dosed rosuvastatin