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4 studies
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- Obesity / overweightHigh cholesterol
Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity
Testing whether daily milk polar lipids affect heart and metabolic risk in adults with belly fat and
📍 University of Connecticut · Storrs, CT · Get directions →
The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.
- High cholesterol
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
Testing how safe and well weekly injections of alirocumab work for high cholesterol in adults
📍 Anaheim Clinical Trials · Anaheim, CA · +29 more US sites · Get directions →
This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels).
- Obesity / overweightHeart / cardiovascular diseaseHigh cholesterol
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
Testing how Akkermansia gut bacteria relate to body and blood lipid changes in people with obesity
📍 London Health Sciences Centre - Victoria Hospital · London, Ontario · Get directions →
The overriding objectives of this study are: 1. Primary outcomes: 1.
- High cholesterolLupus (SLE)
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
Testing certolizumab added to usual treatment to improve pregnancy in lupus and antiphospholipid
📍 Hospital for Special Surgery · New York, NY · +1 more US site · Get directions →
This treatment trial evaluates the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose aspirin) in pregnant women with antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this regimen will improve pregnancy outcomes. All enrolled patients will receive certolizumab, and pregnancy outcomes will be compared to those of women with APS and repeatedly positive tests for LAC enrolled in a previous study by the investigators.