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12 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • Obesity / overweightHigh cholesterol

    Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

    Testing whether daily milk polar lipids affect heart and metabolic risk in adults with belly fat and

    📍 University of Connecticut · Storrs, CT · Get directions →

    The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.

    ✓ Study care freeEarly Phase 1Ages 18–70Learn more →
  • Lupus (SLE)Eczema / atopic dermatitis

    Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

    Testing whether baricitinib is safe in people with Job syndrome and lupus or eczema

    📍 National Institutes of Health Clinical Center · Bethesda, MD · Get directions →

    Background: Autosomal dominant hyper-IgE syndrome (HIES), also called Job syndrome, is a genetic disorder that affects the immune system. It can cause skin and lung infections and problems with blood vessels, connective tissues, and bones.

    ✓ Study care freePhase 1Ages 12–120Learn more →
  • Eczema / atopic dermatitis

    A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)

    Testing BBT001 in healthy adults and adults with eczema

    📍 First OC Dermatology · Irvine, CA · +2 more US sites · Get directions →

    This is a Phase 1, randomized, blinded, placebo controlled, single-ascending dose (SAD) and multiple-ascending dose (MAD) study of BBT001 in healthy volunteers (HVs) and adult patients with moderate to severe Atopic Dermatitis (AD).

    ✓ Study care freePhase 1Ages 18–72Learn more →
  • Eczema / atopic dermatitis

    Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

    Testing a new drug dose in people with eczema and healthy volunteers

    📍 Clinical Site 101 · Fair Lawn, NJ · Get directions →

    This is a first-in-human, Phase 1, double-blind, randomized, placebo-controlled, dose-escalation study evaluating ARQ-234. The study is designed to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ARQ-234 in two populations: healthy volunteers and participants with moderate to severe atopic dermatitis (AD).

    ✓ Study care freePhase 1Ages 18–65Learn more →
  • Eczema / atopic dermatitis

    The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis

    Testing how Botox changes skin immune signals in people with eczema

    📍 University of Pittsburgh Medical Center · Pittsburgh, PA · +1 more US site · Get directions →

    The purpose of this study is to understand cellular and molecular interactions in the skin of participants with mild-to-moderate AD, and how botulinum toxin alters these interactions.

    ✓ Study care freePhase 1Ages 18+Learn more →
  • Eczema / atopic dermatitis

    Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis

    Testing the safety of LPX-TI641 and how the body handles it in eczema

    📍 Red River Research Partners · Fargo, ND · +1 more US site · Get directions →

    The goal of this clinical trial is to study the drug LPX-TI641 in patients with atopic dermatitis and psoriasis. We will compare the safety and tolerability of LPX-TI641 to placebo ( a look-alike solution) that contains no drug.

    ✓ Study care freePhase 1Ages 18+Learn more →
  • Eczema / atopic dermatitis

    FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

    Testing the safety of PF-07832837 in healthy people and eczema patients

    📍 Anaheim Clinical Trials, LLC · Anaheim, CA · +2 more US sites · Get directions →

    The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics of escalating single and repeat doses of PF-07832837 in healthy participants and in participants with moderate to severe atopic dermatitis. An additional goal is to assess the pharmacodynamics of PF-07832837 in participants with moderate to severe AD, including potential effects on clinical signs and symptoms

    ✓ Study care freePhase 1Ages 18–70Learn more →
  • Eczema / atopic dermatitis

    A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis

    Testing how a new medicine works and is tolerated in people with eczema

    📍 Sitryx Clinical Site · Arkansas City, AR · +5 more US sites · Get directions →

    The purpose of this study is to evaluate the study drug, SYX-5219, in a multi-part First-in-Human (FiH) study to be conducted in healthy volunteers and participants with Atopic Dermatitis (AD). The objectives of this study are to determine the safety, tolerability and levels of SYX-5219 in the blood and urine when SYX-5219 is given in each part of the study (SAD, MAD, Food Effect and Participants with AD).

    ✓ Study care freePhase 1Ages 18–65Learn more →
  • Eczema / atopic dermatitis

    Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)

    Testing an approach involving the skin microbiome to treat eczema

    📍 University of California, San Diego: Dermatology Clinical Trials Unit · San Diego, CA · +7 more US sites · Get directions →

    This is a Phase 1b, randomized, placebo/vehicle-controlled, double-blinded, multi-center trial. It is designed to assess the safety and efficacy of S.

    ✓ Study care freePhase 1Ages 6+Learn more →
  • Obesity / overweightHeart / cardiovascular diseaseHigh cholesterol

    Akkermansia Muciniphilia and Metabolic Side Effects of ADT

    Testing how Akkermansia gut bacteria relate to body and blood lipid changes in people with obesity

    📍 London Health Sciences Centre - Victoria Hospital · London, Ontario · Get directions →

    The overriding objectives of this study are: 1. Primary outcomes: 1.

    ✓ Study care freeEarly Phase 1Ages 18+MenLearn more →
  • High cholesterol

    Liver Adiposity Effects on Pediatric Statin

    Measuring how liver fat affects how children take and respond to statin

    📍 Children's Mercy Hospital · Kansas City, MO · Get directions →

    Single center, open-label, prospective investigation to quantify the effects hepatocellular fat has on hepatic statin transport and response in children and adolescents in obese and non-obese children and adolescents 8-21 years of age with normal, wild-type SLCO1B1 c.521TT genotype that are dosed rosuvastatin

    ✓ Study care freePhase 1Ages 8–21Learn more →
  • Eczema / atopic dermatitis

    📍 Arkansas Research Trials · North Little Rock, AR · +2 more US sites · Get directions →

    The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of a single and multiple SC dose of BxC-I17e in patients with moderate to severe atopic dermatitis (AD)

    ✓ Study care freePhase 1Ages 18+Learn more →