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Studies of GLP-1, incretin, and related peptide medications for weight and metabolic health.

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2 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • Dementia / Alzheimer's

    Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease

    Testing a treatment with IL-2 and semaglutide in people with Alzheimer's

    📍 Houston Methodist Research Institute · Houston, TX · Get directions →

    Alzheimer's disease (AD) is the most common cause of dementia. Despite major research efforts, effective treatments that slow or stop disease progression remain limited.

    ✓ Study care freePhase 1Ages 50–86Learn more →
  • Crohn's / ulcerative colitis (IBD)

    Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients

    Testing diet plus an injectable medicine to treat mild Crohn’s in people with higher BMI

    📍 University of Miami · Miami, FL · Get directions →

    The purpose of this study is to use diet and an injectable medication called tirzepatide (Zepbound) glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist (GIP-GLP-1 RA) medication as adjunctive therapy (another treatment used together with the primary treatment) for Crohn's disease patients with mild disease who are on stable doses of biologic medication (infliximab or adalimumab) and who have a body mass index (BMI) of at least 27.

    ✓ Study care freePhase 4Ages 18+Learn more →