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11 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • Migraine / chronic headache

    Mechanistic Studies of Psilocybin in Headache Disorders

    Testing how psilocybin may affect migraine headache symptoms

    📍 VA Connecticut Healthcare System · West Haven, CT · Get directions →

    In previous clinical trial work, the investigators observed lasting reductions in headache burden after limited dosing of psilocybin. This purpose of this study is to examine potential sources for this observed effect.

    ✓ Study care freeEarly Phase 1Ages 21–70Learn more →
  • COPD (chronic lung disease)

    📍 Equity Medical Bowling Green · Bowling Green, KY · +2 more US sites · Get directions →

    Randomized study of single and multiple doses of BBT002 in healthy volunteers and in adult patients with chronic obstructive pulmonary disease (COPD) or chronic rhinosinusitis with nasal polyps (CRSwNP).

    ✓ Study care freePhase 1Ages 18–80Learn more →
  • COPD (chronic lung disease)

    A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

    Testing the safety and effects of an inhaled medicine for COPD

    📍 University of Alabama at Birmingham · Birmingham, AL · +6 more US sites · Get directions →

    This study evaluates the safety, tolerability, and activity of inhaled GDC-6988 in participants with muco-obstructive disease.

    ✓ Study care freePhase 1Ages 18+Learn more →
  • Obesity / overweightHigh blood pressureCOPD (chronic lung disease)

    Feasibility of Semaglutide in Advanced Lung Disease

    Testing whether semaglutide can be given safely to people with advanced lung disease

    📍 University of Pennsylvania Perelman School of Medicine · Philadelphia, PA · Get directions →

    The goal of this clinical trial is to learn whether semaglutide, an FDA-approved treatment for diabetes and obesity, is feasible and tolerable in patients with advanced lung disease. The main question\[s\] it aims to answer are: 1.

    ✓ Study care freePhase 1Ages 18–80Learn more →
  • Migraine / chronic headache

    Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?

    Testing whether a nerve block plus steroid tablets lowers migraine headache return within 72 hours

    📍 University Medical Center of El Paso · El Paso, TX · Get directions →

    For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.

    ✓ Study care freeEarly Phase 1Ages 18–85Learn more →
  • Heart / cardiovascular diseaseHigh blood pressureCOPD (chronic lung disease)

    : Vascular Function in Health and Disease

    Studying how blood vessel function works in health and diseases like heart problems, high blood

    📍 George E Wahlen VA Medical Center · Salt Lake City, UT · Get directions →

    Many control mechanisms exist which successfully match the supply of blood with the metabolic demand of various tissues under wide-ranging conditions. One primary regulator of vasomotion and thus perfusion to the muscle tissue is the host of chemical factors originating from the vascular endothelium and the muscle tissue, which collectively sets the level of vascular tone.

    ✓ Study care freePhase 1Ages 18+Learn more →
  • COPD (chronic lung disease)

    Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy

    Comparing a lung scan that uses xenon MRI with a radioactive scan for COPD

    📍 University of Virginia Health System · Charlottesville, VA · Get directions →

    Hyper polarized Xenon-129 MRI will be directly compared to a radioactive Xe-133 scintigraphy to detect defects in lung ventilation from airflow limitation. This study is conducted as a pilot study with intention to conduct a larger clinical trial.

    ✓ Study care freePhase 1Ages 18+Learn more →
  • COPD (chronic lung disease)

    Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

    Testing whether lung transplant first can improve lung function before bone marrow transplant for

    📍 UPMC Presbyterian · Pittsburgh, PA · +1 more US site · Get directions →

    The purpose of this study is to determine whether a lung transplantation prior to bone marrow transplantation (BMT) would allow for restoration of pulmonary function prior to BMT, allowing to proceed to BMT, to restore hematologic function.

    ✓ Study care freePhase 1Ages 18–60Learn more →
  • High blood pressureCOPD (chronic lung disease)Asthma

    Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

    Testing a lung scan method using hyperpolarized oxygen gas MRI in healthy and people with COPD or

    📍 University of Kansas Medical Center · Kansas City, KS · Get directions →

    The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.

    ✓ Study care freePhase 1Ages 3+Learn more →
  • COPD (chronic lung disease)Asthma

    Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Pulmonary Diseases

    Testing the safety of an IV stem cell treatment for lung diseases like COPD and asthma

    📍 Medical Surgical Associates Center · St John's, · Get directions →

    This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Pulmonary Diseases

    ✓ Study care freePhase 1Learn more →
  • Migraine / chronic headache

    A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

    Testing safety and how zavegepant is processed in children with migraine

    📍 Arkansas Children's Hospital · Little Rock, AR · +12 more US sites · Get directions →

    The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study helps understand how the medicine is changed and removed from the body after taking it.

    ✓ Study care freePhase 1Ages 6–11Learn more →