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Studies of GLP-1, incretin, and related peptide medications for weight and metabolic health.
2 studies
Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Migraine / chronic headache
Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications
Testing whether a migraine attack medicine works and is tolerated in people using preventive CGRP
📍 Mayo Clinic in Arizona · Phoenix, AZ · Get directions →
Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.
- Kidney disease
Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis
Testing whether a weekly diabetes medicine is safe for people on dialysis
📍 Unity Health Toronto · Toronto, Ontario · Get directions →
This study aims to determine if GLP1RA is safe and tolerable in maintenance dialysis population, adherence, and feasibility of a larger definitive cardiovascular outcome trial in this population. Participants will be randomized 1:1 to either weekly subcutaneous semaglutide versus usual care and followed for 26 weeks.