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8 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • Obesity / overweightHigh cholesterol

    Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

    Testing whether daily milk polar lipids affect heart and metabolic risk in adults with belly fat and

    📍 University of Connecticut · Storrs, CT · Get directions →

    The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.

    ✓ Study care freeEarly Phase 1Ages 18–70Learn more →
  • Type 2 diabetesHeart / cardiovascular disease

    Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

    Testing how drinking ketone drinks affects heart function in people with type 2 diabetes and heart

    📍 University of Texas Health Science Center at San Antonio · San Antonio, TX · Get directions →

    This study will provide insight into whether cardiac function changes with oral Ketone Esters (KE) administered to patients with Type 2 Diabetes Mellitus (T2DM) and Heart failure with reduced ejection fraction (HFrEF). Plasma ketones are avidly extracted by cardiac muscle and their uptake is not dependent upon insulin or influenced by insulin resistance.

    ✓ Study care freeEarly Phase 1Ages 18–80Learn more →
  • Asthma

    Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation

    Testing early IV magnesium sulfate for people with a moderate asthma flare

    📍 Oklahoma Children's Hospital · Oklahoma City, OK · Get directions →

    This study aims to identify whether early administration of magnesium sulfate in moderate asthma exacerbations can potentially avoid admission, decrease length of stay in the emergency department (ED), decrease length of stay (LOS) in the general hospital floor vs pediatric intensive care unit (PICU), and decrease the need for respiratory support.

    ✓ Study care freeEarly Phase 1Ages 5–17Learn more →
  • Migraine / chronic headache

    Mechanistic Studies of Psilocybin in Headache Disorders

    Testing how psilocybin may affect migraine headache symptoms

    📍 VA Connecticut Healthcare System · West Haven, CT · Get directions →

    In previous clinical trial work, the investigators observed lasting reductions in headache burden after limited dosing of psilocybin. This purpose of this study is to examine potential sources for this observed effect.

    ✓ Study care freeEarly Phase 1Ages 21–70Learn more →
  • Obesity / overweightHigh blood pressure

    Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension

    Testing whether angiotensin-(1-7) affects heart health in people with obesity and high blood

    📍 Penn State Milton S. Hershey Medical Center · Hershey, PA · Get directions →

    Obesity is a global health concern that is associated with high blood pressure and an increased risk for developing cardiovascular disease. The purpose of this study is to find out if the investigational drug angiotensin-(1-7) can improve cardiovascular health in people with obesity and high blood pressure.

    ✓ Study care freeEarly Phase 1Ages 18–65Learn more →
  • Obesity / overweightHeart / cardiovascular diseaseHigh cholesterol

    Akkermansia Muciniphilia and Metabolic Side Effects of ADT

    Testing how Akkermansia gut bacteria relate to body and blood lipid changes in people with obesity

    📍 London Health Sciences Centre - Victoria Hospital · London, Ontario · Get directions →

    The overriding objectives of this study are: 1. Primary outcomes: 1.

    ✓ Study care freeEarly Phase 1Ages 18+MenLearn more →
  • Migraine / chronic headache

    Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?

    Testing whether a nerve block plus steroid tablets lowers migraine headache return within 72 hours

    📍 University Medical Center of El Paso · El Paso, TX · Get directions →

    For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.

    ✓ Study care freeEarly Phase 1Ages 18–85Learn more →
  • Obesity / overweightHigh blood pressure

    Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)

    Studying how the nervous system controls blood pressure in obesity and high blood pressure

    📍 University of Texas Southwestern Medical Center · Dallas, TX · Get directions →

    The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress. The study will also investigate how hypertension and obesity influence the nervous system and vascular function.

    ✓ Study care freeEarly Phase 1Ages 18–55Learn more →