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8 studies
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- Dementia / Alzheimer's💵 May compensate
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
Testing a brain stimulation approach to study memory and thinking in people with early
📍 Massachusetts General Hospital · Charlestown, MA · Get directions →
The project is a placebo-controlled study that aims to use closed-loop transcranial alternating current stimulation (tACS) to study patients with symptoms of mild cognitive impairment which is likely due to Alzheimer's disease or another form of dementia (AD-MCI). Patients will undergo an EEG and complete some questionnaires and computer tasks during each study visit.
- Dementia / Alzheimer's💵 May compensate
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Testing an Alzheimer’s treatment in people with dementia and gum infection
📍 Banner Alzheimer's Institute · Phoenix, AZ · +38 more US sites · Get directions →
This study is to test LHP588 in persons who have mild to moderate Alzheimer's disease (AD) who have shown progressive mental decline in the last year and who have P. gingivalis (Pg) infection.
- Sickle cell disease💵 May compensate
Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease
Testing higher doses of VAS-101 in people with stable sickle cell disease
📍 National Institutes of Health Clinical Center · Bethesda, MD · Get directions →
Background: Sickle cell disease (SCD) is an inherited blood disorder. The disease affects the ability of red blood cells to carry oxygen.
- Sickle cell disease💵 May compensate
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
Testing whether acupuncture can reduce pain in people with sickle cell disease
📍 Indiana University School of Medicine · Indianapolis, IN · Get directions →
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Dementia / Alzheimer's💵 May compensate
Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1
Testing a brain scan tracer to measure inflammation in dementia
📍 Washington University School of Medicine · St Louis, MO · Get directions →
This study involves a brain positron emission tomography (PET) scan with a new, investigational radioactive tracer called \[11C\]-CS1P1 to identify inflammation in the brain by testing with healthy older adults and with cognitively impaired older adults.
- Dementia / Alzheimer's💵 May compensate
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Testing an online speech and language program to improve communication and quality of life for
📍 University of Texas · Austin, TX · Get directions →
The goal of this clinical trial is to learn whether a personalized, multi-component, virtual speech language treatment program can improve communication and quality of life for adults with primary progressive aphasia (PPA) and their primary communication partners. The study will enroll participants who speak English and/or Spanish.
- Parkinson's disease💵 May compensate
SAD Study in Patients With Parkinson's Disease and Motor Fluctuations
Testing a single dose of SER-252 in people with Parkinson’s disease
📍 Rocky Mountain Clinical Research · Englewood, CO · +3 more US sites · Get directions →
This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.
- Parkinson's disease💵 May compensate
Blood Pressure Effects on Cognition and Brain Blood Flow in PD
Testing how blood pressure in Parkinson’s affects thinking and brain blood flow
📍 University of California San Diego · San Diego, CA · Get directions →
Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension (OH), i.e., low blood pressure (BP) when standing.