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9 studies
Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Rheumatoid arthritis💵 May compensate
Targeted Remotely-delivered Anti-inflammatory Interventions With Exercise for Rheumatoid Arthritis
Testing a remote exercise program (aerobic and strength) for people with rheumatoid arthritis
📍 Duke University · Durham, NC · Get directions →
The primary objective of this study is to assess the feasibility of an intensive, remotely-delivered, combined aerobic and resistance training exercise program for patients with Rheumatoid Arthritis (RA) and to collect data to support power calculations for a larger research study.
- Dementia / Alzheimer's💵 May compensate
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
Testing a brain stimulation approach to study memory and thinking in people with early
📍 Massachusetts General Hospital · Charlestown, MA · Get directions →
The project is a placebo-controlled study that aims to use closed-loop transcranial alternating current stimulation (tACS) to study patients with symptoms of mild cognitive impairment which is likely due to Alzheimer's disease or another form of dementia (AD-MCI). Patients will undergo an EEG and complete some questionnaires and computer tasks during each study visit.
- Dementia / Alzheimer's💵 May compensate
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Testing an Alzheimer’s treatment in people with dementia and gum infection
📍 Banner Alzheimer's Institute · Phoenix, AZ · +38 more US sites · Get directions →
This study is to test LHP588 in persons who have mild to moderate Alzheimer's disease (AD) who have shown progressive mental decline in the last year and who have P. gingivalis (Pg) infection.
- Dementia / Alzheimer's💵 May compensate
Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1
Testing a brain scan tracer to measure inflammation in dementia
📍 Washington University School of Medicine · St Louis, MO · Get directions →
This study involves a brain positron emission tomography (PET) scan with a new, investigational radioactive tracer called \[11C\]-CS1P1 to identify inflammation in the brain by testing with healthy older adults and with cognitively impaired older adults.
- Dementia / Alzheimer's💵 May compensate
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Testing an online speech and language program to improve communication and quality of life for
📍 University of Texas · Austin, TX · Get directions →
The goal of this clinical trial is to learn whether a personalized, multi-component, virtual speech language treatment program can improve communication and quality of life for adults with primary progressive aphasia (PPA) and their primary communication partners. The study will enroll participants who speak English and/or Spanish.
- Parkinson's disease💵 May compensate
SAD Study in Patients With Parkinson's Disease and Motor Fluctuations
Testing a single dose of SER-252 in people with Parkinson’s disease
📍 Rocky Mountain Clinical Research · Englewood, CO · +3 more US sites · Get directions →
This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.
- Parkinson's disease💵 May compensate
Blood Pressure Effects on Cognition and Brain Blood Flow in PD
Testing how blood pressure in Parkinson’s affects thinking and brain blood flow
📍 University of California San Diego · San Diego, CA · Get directions →
Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension (OH), i.e., low blood pressure (BP) when standing.
- Migraine / chronic headache💵 May compensate
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
Studying real-world results of migraine preventive medicines targeting CGRP
📍 University of Miami, Miller School of Medicine · Miami, FL · Get directions →
The goal of this observational study is to evaluate clinical differences in patients who received preventive treatment with medication targeting calcitonin gene-related peptide (CGRP) or its receptor: monoclonal antibodies (erenumab, galcanezumab, fremanezumab, eptinezumab) or gepants (rimegepant, atogepant) during a 2-year period observation phase.
- Rheumatoid arthritis💵 May compensate
EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))
Studying how well a hip replacement cup is positioned in people with rheumatoid arthritis using
📍 UC Davis Health System · Sacramento, CA · +4 more US sites · Get directions →
The purpose of this research is to gather clinical and radiographic (X-ray) information about EMPHASYS™ acetabular shell (also called a hip 'cup') placement in total hip replacement surgery using a non-invasive surgical navigation system called VELYS™ hip navigation system with CUPTIMIZE™ Advanced Hip-Spine Analysis software. Data collected in this study will be compared with data collected from implantations using different cup positioning instrumentation and techniques to assess performance.