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9 studies

Recruiting now, in plain language. Every study is watched over by an independent ethics board.

  • High blood pressure

    Arterial Ablation for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities

    Testing a device used through a blood-vessel procedure for type 2 diabetes and high blood pressure

    💵 May compensate

    📍 Hospital Paitilla Clinicas y Hospitales · Panama City, · Get directions →

    This study is assess the safety and performance of the Neurotronic Infusion catheter for treatment of patients with Type 2 Diabetes (T2DM) and hypertension.

    ✓ Study care freePhase 1Ages 21–65Learn more →
  • COPD (chronic lung disease)

    PiMZ Longitudinal Cohort (PiMZ Logic)

    Tracking how COPD affects people with the PiMZ form of alpha-1 anti-trypsin deficiency

    💵 May compensate

    📍 University of Alabama at Birmingham · Birmingham, AL · +4 more US sites · Get directions →

    Alpha-1 Anti-trypsin Deficiency (AATD) is a genetic disease with lung and liver disease presentations. Presentations are variable in the heterozygous population, the most predominant genotype being PiMZ.

    ✓ Study care freeAges 18+Learn more →
  • COPD (chronic lung disease)

    Effect of the Inhaled Triple Therapies Over the Small Airway in Biomass Exposure

    Comparing inhaled triple versus double medicines for COPD lung airways after wood smoke exposure

    💵 May compensate

    📍 Insituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas" · Mexico City, Tlalpan · Get directions →

    This phase IV randomized controlled clinical trial intend to compare the effect of three close standard inhaled triple therapies and one close standard inhaled double therapy on the small airway in patients with Chronic Obstructive Pulmonary Disease (COPD-B) and chronic bronchitis without obstruction (BCNO) exposed to wood smoke. The treatment phase duration is of 3 months.

    ✓ Study care freePhase 4Ages 35–85WomenLearn more →
  • Obesity / overweightHigh blood pressure

    Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

    Testing treatments to lower high pressure in liver veins in people with advanced liver disease and

    💵 May compensate

    📍 Cleveland Clinic Main Campus · Cleveland, OH · Get directions →

    Cirrhosis is a form of advanced liver disease that can lead to serious complications, especially when combined with severe obesity. Many patients with cirrhosis also develop a condition called clinically significant portal hypertension (CSPH), which is increased pressure in the veins of the liver.

    ✓ Study care freePhase 4Ages 18–70Learn more →
  • COPD (chronic lung disease)

    Routine vs On-demand ECMO for Lung Transplantation

    Comparing routine versus on-demand ECMO during lung transplants for people with COPD

    💵 May compensate

    📍 Univeristy of Alberta & Alberta Health Services · Edmonton, Alberta · Get directions →

    Lung transplantation is a complex procedure performed in patients with terminal lung disease. The transplant procedure stresses the patient's heart and lungs, which are already taxed by the underlying disease process.

    ✓ Study care freeAges 18+Learn more →
  • COPD (chronic lung disease)

    Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

    Testing a lung procedure to reduce lung trapping in severe COPD

    💵 May compensate

    📍 Beth Israel Deaconess Medical Center · Boston, MA · Get directions →

    The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental intervention) in severe emphysema/COPD patients with failed bronchoscopic lung volume reduction (BLVR) via the use of endobronchial valves (EBVs) therapy. In select patients, the lung fissure completion with adhesiolysis strategy will be performed by video-assisted thoracoscopic surgery (VATS) guided stapling along the lung fissures to reduce collateral ventilation with adhesions removal and determine whether this experimental strategy will improve outcomes after failed BLVR in patients with severe emphysema/COPD.

    ✓ Study care freeAges 40–75Learn more →
  • COPD (chronic lung disease)

    Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

    Studying whether sleep apnea together with COPD affects thinking in older veterans

    💵 May compensate

    📍 John D. Dingell VA Medical Center, Detroit, MI · Detroit, MI · Get directions →

    Cognitive dysfunction in the aging Veteran population is a growing health concern in the Veterans Health System. It is not known whether OSA coexisting with COPD will enhance the risk for cognitive dysfunction.

    ✓ Study care freeAges 60–89Learn more →
  • COPD (chronic lung disease)
    💵 May compensate

    📍 University of Tennessee Medical Center · Knoxville, TN · Get directions →

    The purpose of this study is to assess the feasibility, safety and efficacy of a combination of nebulized Formoterol and Revefenacin among patients hospitalized for AECOPD compared with standard-of-care therapy with nebulized Albuterol and Ipratropium.

    ✓ Study care freePhase 4Ages 40+Learn more →
  • COPD (chronic lung disease)

    Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo

    Studying how adults with COPD feel and how their symptoms change over time

    💵 May compensate

    📍 Research Site · Buenos Aires, · Get directions →

    Chronic Obstructive Pulmonary Disease is a leading cause of global morbidity and mortality, especially in low- and middle-income countries. Exacerbations accelerate disease progression and increase the risk of death.

    ✓ Study care freeAges 30–80Learn more →