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8 studies
Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Dementia / Alzheimer's💵 May compensate
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Testing an Alzheimer’s treatment in people with dementia and gum infection
📍 Banner Alzheimer's Institute · Phoenix, AZ · +38 more US sites · Get directions →
This study is to test LHP588 in persons who have mild to moderate Alzheimer's disease (AD) who have shown progressive mental decline in the last year and who have P. gingivalis (Pg) infection.
- DepressionAnxiety💵 May compensate
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
Testing psilocybin-assisted therapy for depression and anxiety in people with advanced cancer
📍 MD Anderson Cancer Center · Houston, TX · Get directions →
To learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy on depression and/or anxiety in participants who are being treated for advanced cancer.
- Depression💵 May compensate
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
Testing ketamine infusions plus brief counseling for veterans with low back pain and depression
📍 VA Ann Arbor Healthcare System, Ann Arbor, MI · Ann Arbor, MI · Get directions →
This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.
- DepressionAnxiety💵 May compensate
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
Testing psilocybin-assisted therapy for depression and anxiety in cancer survivors
📍 The University of Texas M. D. Anderson Cancer Center · Houston, TX · Get directions →
This clinical research study is to learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy for cancer survivors with depression and/or anxiety.
- COPD (chronic lung disease)💵 May compensate
Effect of the Inhaled Triple Therapies Over the Small Airway in Biomass Exposure
Comparing inhaled triple versus double medicines for COPD lung airways after wood smoke exposure
📍 Insituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas" · Mexico City, Tlalpan · Get directions →
This phase IV randomized controlled clinical trial intend to compare the effect of three close standard inhaled triple therapies and one close standard inhaled double therapy on the small airway in patients with Chronic Obstructive Pulmonary Disease (COPD-B) and chronic bronchitis without obstruction (BCNO) exposed to wood smoke. The treatment phase duration is of 3 months.
- DepressionAnxiety💵 May compensate
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
Testing whether pregnenolone pills affect brain function and depression in people with HIV
📍 Massachusetts General Hospital · Boston, MA · Get directions →
This study will determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression. Participants in this study will receive a pill of either pregnenolone or placebo, and can stay on their current antidepression medications.
- Depression💵 May compensate
Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility Trial
Testing whether a brain response to L-DOPA can track outcomes in late-life depression
📍 St. Paul's Hospital · Vancouver, British Columbia · Get directions →
Background Adults over the age of 60 with symptoms of major depressive disorder are said to have late-life depression (LLD), a condition that usually decreases a person's quality of life and is associated with other risks like physical frailty and dementia. A common feature of more severe LLD is psychomotor slowing, where a person's ability to think and move are impaired.
- COPD (chronic lung disease)💵 May compensate
Feasibility, Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPD
Testing nebulized long-acting breathing medicines vs usual short-acting ones in hospitalized COPD
📍 University of Tennessee Medical Center · Knoxville, TN · Get directions →
The purpose of this study is to assess the feasibility, safety and efficacy of a combination of nebulized Formoterol and Revefenacin among patients hospitalized for AECOPD compared with standard-of-care therapy with nebulized Albuterol and Ipratropium.