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- COPD (chronic lung disease)
Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo
💵 May compensate📍 Research Site · Buenos Aires, · Get directions →
Chronic Obstructive Pulmonary Disease is a leading cause of global morbidity and mortality, especially in low- and middle-income countries. Exacerbations accelerate disease progression and increase the risk of death.
- COPD (chronic lung disease)
PiMZ Longitudinal Cohort (PiMZ Logic)
💵 May compensate📍 University of Alabama at Birmingham · Birmingham, AL · +4 more US sites · Get directions →
Alpha-1 Anti-trypsin Deficiency (AATD) is a genetic disease with lung and liver disease presentations. Presentations are variable in the heterozygous population, the most predominant genotype being PiMZ.
- COPD (chronic lung disease)
Routine vs On-demand ECMO for Lung Transplantation
💵 May compensate📍 Univeristy of Alberta & Alberta Health Services · Edmonton, Alberta · Get directions →
Lung transplantation is a complex procedure performed in patients with terminal lung disease. The transplant procedure stresses the patient's heart and lungs, which are already taxed by the underlying disease process.
- COPD (chronic lung disease)
Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction
💵 May compensate📍 Beth Israel Deaconess Medical Center · Boston, MA · Get directions →
The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental intervention) in severe emphysema/COPD patients with failed bronchoscopic lung volume reduction (BLVR) via the use of endobronchial valves (EBVs) therapy. In select patients, the lung fissure completion with adhesiolysis strategy will be performed by video-assisted thoracoscopic surgery (VATS) guided stapling along the lung fissures to reduce collateral ventilation with adhesions removal and determine whether this experimental strategy will improve outcomes after failed BLVR in patients with severe emphysema/COPD.
- COPD (chronic lung disease)
Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
💵 May compensate📍 John D. Dingell VA Medical Center, Detroit, MI · Detroit, MI · Get directions →
Cognitive dysfunction in the aging Veteran population is a growing health concern in the Veterans Health System. It is not known whether OSA coexisting with COPD will enhance the risk for cognitive dysfunction.
- COPD (chronic lung disease)
📍 Insituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas" · Mexico City, Tlalpan · Get directions →
This phase IV randomized controlled clinical trial intend to compare the effect of three close standard inhaled triple therapies and one close standard inhaled double therapy on the small airway in patients with Chronic Obstructive Pulmonary Disease (COPD-B) and chronic bronchitis without obstruction (BCNO) exposed to wood smoke. The treatment phase duration is of 3 months.