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12 studies
Recruiting now, in plain language. Every study is watched over by an independent ethics board.
- Multiple sclerosis (MS)💵 May compensate
This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.
Testing a new brain PET scan tracer to detect inflammation in multiple sclerosis
📍 Washington University in St. Louis · St Louis, MO · Get directions →
This study involves a Positron Emission Tomography (PET) scan using a new investigational radioactive tracer, \[18F\]-FZTA, to detect inflammation in the brain. The tracer will be tested in healthy younger adults and individuals with Multiple Sclerosis.
- Dementia / Alzheimer's💵 May compensate
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
Testing a brain stimulation approach to study memory and thinking in people with early
📍 Massachusetts General Hospital · Charlestown, MA · Get directions →
The project is a placebo-controlled study that aims to use closed-loop transcranial alternating current stimulation (tACS) to study patients with symptoms of mild cognitive impairment which is likely due to Alzheimer's disease or another form of dementia (AD-MCI). Patients will undergo an EEG and complete some questionnaires and computer tasks during each study visit.
- Dementia / Alzheimer's💵 May compensate
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Testing an Alzheimer’s treatment in people with dementia and gum infection
📍 Banner Alzheimer's Institute · Phoenix, AZ · +38 more US sites · Get directions →
This study is to test LHP588 in persons who have mild to moderate Alzheimer's disease (AD) who have shown progressive mental decline in the last year and who have P. gingivalis (Pg) infection.
- Anxiety💵 May compensate
Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study
Testing a wearable brain stimulation device to treat anxiety in veterans
📍 Birmingham VA · Birmingham, AL · Get directions →
Transcranial alternating current stimulation (tACS) in a wearable brain stimulation device that delivers a low intensity, pulsed, alternating current via scalp electrodes. Prior sham-controlled clinical trials have shown the therapeutic effects and safety of tACS for the treatment of anxiety and depression.
- Anxiety💵 May compensate
Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings
Testing different ways to deliver talk therapy skills for kids with anxiety
📍 Bradley Hospital · East Providence, RI · Get directions →
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness. CBT involves teaching the patient skills to enable them to gradually come into contact with feared situations.
- Dementia / Alzheimer's💵 May compensate
Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1
Testing a brain scan tracer to measure inflammation in dementia
📍 Washington University School of Medicine · St Louis, MO · Get directions →
This study involves a brain positron emission tomography (PET) scan with a new, investigational radioactive tracer called \[11C\]-CS1P1 to identify inflammation in the brain by testing with healthy older adults and with cognitively impaired older adults.
- Anxiety💵 May compensate
Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders
Testing a non-invasive brain stimulation device to help treat mealtime anxiety in adults with eating
📍 Rogers Behavioral Health · Oconomowoc, WI · Get directions →
The study is to evaluate the feasibility of using a non-invasive brain stimulation device in a sample of inpatients with eating disorders (ED). The study will help researchers evaluate whether their device protocol is practical for eating disorder inpatients as a way to manage eating disorder and anxiety symptoms.
- Dementia / Alzheimer's💵 May compensate
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Testing an online speech and language program to improve communication and quality of life for
📍 University of Texas · Austin, TX · Get directions →
The goal of this clinical trial is to learn whether a personalized, multi-component, virtual speech language treatment program can improve communication and quality of life for adults with primary progressive aphasia (PPA) and their primary communication partners. The study will enroll participants who speak English and/or Spanish.
- DepressionAnxiety💵 May compensate
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
Testing psilocybin-assisted therapy for depression and anxiety in people with advanced cancer
📍 MD Anderson Cancer Center · Houston, TX · Get directions →
To learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy on depression and/or anxiety in participants who are being treated for advanced cancer.
- DepressionAnxiety💵 May compensate
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
Testing psilocybin-assisted therapy for depression and anxiety in cancer survivors
📍 The University of Texas M. D. Anderson Cancer Center · Houston, TX · Get directions →
This clinical research study is to learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy for cancer survivors with depression and/or anxiety.
- Multiple sclerosis (MS)💵 May compensate
Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod
Testing whether ozanimod is safe and works as a step-down treatment for stable multiple sclerosis
📍 University of Colorado Anschutz Medical Campus · Aurora, CO · +2 more US sites · Get directions →
A multi-center pilot study to evaluate safety and efficacy of ozanimod as de-escalation therapy in clinically stable MS patients previously treated with anti-CD20 therapy.
- DepressionAnxiety💵 May compensate
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
Testing whether pregnenolone pills affect brain function and depression in people with HIV
📍 Massachusetts General Hospital · Boston, MA · Get directions →
This study will determine the effects of pregnenolone on brain function, inflammation and depressive symptoms in people with HIV who have depression. Participants in this study will receive a pill of either pregnenolone or placebo, and can stay on their current antidepression medications.