Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
Recruiting · 10 sites across 8 states
Always free
Study care at no cost to you
For your time and travel
Many studies pay you back
Most need no insurance or papers
Legal status usually isn't required; we'll tell you each study's requirements
Interpreters available
Ask for your language
Your choice
Voluntary — you can stop anytime
What is this study?
This study is a Phase 2 clinical trial to evaluate the efficacy, safety, and tolerability of HM15275 in subjects with type 2 diabetes mellitus over 36 weeks.
It is , overseen by an independent and licensed medical staff.
Read the full clinical description
This study is a Phase 2 clinical trial to evaluate the efficacy, safety, and tolerability of HM15275 in subjects with type 2 diabetes mellitus over 36 weeks.
Who this study is looking for
In plain language, from the study's own rules. The study team confirms the full details with you — this isn't a final yes or no.
✅ You may be able to join if…
- •Ages 18 to 75 (inclusive)
- •Diagnosed with type 2 diabetes mellitus (type 2 diabetes) with HbA1c between 7.0% and 10.0% at screening
- •Taking diet and exercise only or a stable dose of metformin (at least 1000 mg/day) for at least 3 months
- •BMI between 25 and 50 kg/m²
- •Able to give signed informed consent and follow study procedures
🚫 You may not be able to join if…
- •Have type 1 diabetes or have used other glucose-lowering medicines besides metformin within 3 months of screening
- •Have poor glycemic control (fasting plasma glucose >270 mg/dL)
- •Had diabetic ketoacidosis or severe hypoglycemia within the last 6 months
- •Have certain cardiovascular problems (including NYHA class III/IV heart failure, or a heart attack, stroke, or revascularization within 3 months)
- •Have conditions that increase pancreas risk, thyroid cancer risk (MTC or MEN type 2), significant liver disease, kidney impairment (eGFR <60 mL/min/1.73 m²), or abnormal screening lab results
Are you a good fit?
Simplified highlights. The study team always confirms the full details with you.
- ✓Adults roughly 18–75
- ✓A BMI around 25 or higher
- ✓Have Obesity / overweight or Type 2 diabetes
- !Some conditions may not be a fit: Heart / cardiovascular disease, Kidney disease
- !May require a break from current GLP-1 medications
What to expect, step by step
- 1
Usually a few weeks
The study team checks whether the study is a good fit for you, with a visit and sometimes lab tests. You can ask any questions before deciding.
- 2
Treatment
If you join and choose to continue, you receive the study treatment and are watched closely by medical staff.
- 3
Follow-up
After treatment, the team checks on your health and confirms the visit schedule with you. You can leave the study at any point.
Has this treatment been tested before?
Yes. This treatment has already been through earlier human studies for safety before reaching this stage.
What you need to know before you apply
What is this study testing?+
This study is a Phase 2 clinical trial to evaluate the efficacy, safety, and tolerability of HM15275 in subjects with type 2 diabetes mellitus over 36 weeks.
Is it safe? Who makes sure of that?+
This is a mid-stage study (Phase 2), looking at safety and whether the treatment works. Every study is reviewed and monitored by an independent ethics board (called an IRB) whose job is to protect participants, and care is overseen by licensed medical staff. You'll be told the known risks before you agree to anything, and you can stop at any time.
Will I get a placebo instead of the real treatment?+
Some studies compare a treatment against a placebo (an inactive version), and some don't. If this one does, the study team will explain your chances of receiving the active treatment before you decide. Nothing is hidden from you.
I take a GLP-1 medication (like Ozempic or Wegovy). Can I still join?+
Maybe. This study may ask you to pause certain weight or diabetes medications for a period of time (a 'washout') before joining, or it may be looking for people not currently on them. The coordinator will review your medications with you — don't stop any medication on your own.
Does it cost anything? Will I be paid?+
The study treatment and study-related visits are provided at no cost to you. Some studies also pay for your time; the coordinator can tell you if this one does. You should never be asked to pay to take part.
Do I need insurance? Will anyone ask about my immigration status?+
No. You do not need health insurance to take part in a research study, and you will not be asked about your immigration status to join. Taking part is about whether you're a medical fit for the study.
What if English isn't my first language?+
You have the right to understand everything before you agree. Study sites can often provide materials or an interpreter in your language — you can ask the coordinator for one.
Is my information private?+
Yes. Your health information is only shared with the study sites you choose to be contacted by, and only to help match and enroll you. It is never sold, and you can ask us to delete it at any time.
Some requirements (like specific lab values or timing) are confirmed directly by the study team, not by us.
Source: ClinicalTrials.gov · NCT07527650 · Locations: Arizona · Florida · Indiana · Missouri · Nebraska · Nevada · North Carolina · Utah