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Obesity / overweightType 2 diabetes

Effects of HIIT vs. TRE on Type 2 Diabetes Risk

Recruiting · Syracuse, New York

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Your choice

Voluntary — you can stop anytime

What is this study?

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.

It is , overseen by an independent and licensed medical staff.

Read the full clinical description

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.

Who this study is looking for

In plain language, from the study's own rules. The study team confirms the full details with you — this isn't a final yes or no.

✅ You may be able to join if…

  • Adolescents ages 14 to 17 years old
  • Adolescents with a BMI percentile at or above the 85th percentile for their sex and race
  • Young adults ages 18 to 30 years old
  • Young adults with overweight/obesity (BMI at least 25 kg/m²)

🚫 You may not be able to join if…

  • People with chronic medical conditions such as heart disease, arrhythmias, diabetes, thyroid disease, or hypertension
  • People with chronic lung disease/history of pulmonary disease
  • People with bleeding disorders, anemia, autoimmune disease, cancer, peptic ulcers, or chronic infection (HIV)
  • People who have taken certain medicines (heart, thyroid, anti-hyperlipidemic, diabetes-related, blood pressure, emotional/psychotropic, neuromuscular/neurological, or androgenic/anabolic steroid medicines)
  • People with a pacemaker

Are you a good fit?

Simplified highlights. The study team always confirms the full details with you.

  • Aged 14 to 30 years
  • Has overweight/obesity: BMI at least 25 kg/m² (or BMI percentile ≥85th if 14–17)
  • Has type 2 diabetes
  • Does not have significant heart/circulatory conditions (coordinator confirms)
  • Not using certain heart/lung/thyroid/diabetes/blood pressure or other listed medications (coordinator confirms)
  • !Some conditions may not be a fit: High blood pressure

How this study is designed

The real details, in plain words. Tap the underlined words to learn what they mean.

  • Everyone in this study receives an active treatment — there is no placebo group.
  • You'd be placed into a group by chance, like a coin flip — this keeps the study fair.
  • There are 3 groups in this study.

What to expect, step by step

· This study lasts about 4 weeks
  1. 1

    Usually a few weeks

    The study team checks whether the study is a good fit for you, with a visit and sometimes lab tests. You can ask any questions before deciding.

  2. 2

    Treatment

    About 4 weeks

    If you join and choose to continue, you receive the study treatment and are watched closely by medical staff.

  3. 3

    Follow-up

    After treatment, the team checks on your health and confirms the visit schedule with you. You can leave the study at any point.

What's being tested

  • Behavioral: High-intensity interval training
  • Behavioral: Time-restricted eating

Has this treatment been tested before?

The study team can share what safety testing has been done so far.

Who's running this study?

Sponsor

Syracuse University

Every study is also reviewed by an independent that protects participants.

What you need to know before you apply

What is this study testing?+

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.

Is it safe? Who makes sure of that?+

This is a research study. Every study is reviewed and monitored by an independent ethics board (called an IRB) whose job is to protect participants, and care is overseen by licensed medical staff. You'll be told the known risks before you agree to anything, and you can stop at any time.

Will I get a placebo instead of the real treatment?+

Some studies compare a treatment against a placebo (an inactive version), and some don't. If this one does, the study team will explain your chances of receiving the active treatment before you decide. Nothing is hidden from you.

Do I have to stop taking my current medications?+

It depends on the study. Some let you stay on your current medications and some ask you to adjust them. Never stop a medication on your own — the study team will review everything with you first.

Does it cost anything? Will I be paid?+

Study-related care is provided at no cost to you. Some studies also pay for your time; the coordinator can tell you if this one does. You should never be asked to pay to take part.

Do I need insurance? Will anyone ask about my immigration status?+

No. You do not need health insurance to take part in a research study, and you will not be asked about your immigration status to join. Taking part is about whether you're a medical fit for the study.

What if English isn't my first language?+

You have the right to understand everything before you agree. Study sites can often provide materials or an interpreter in your language — you can ask the coordinator for one.

Is my information private?+

Yes. Your health information is only shared with the study sites you choose to be contacted by, and only to help match and enroll you. It is never sold, and you can ask us to delete it at any time.

Some requirements (like specific lab values or timing) are confirmed directly by the study team, not by us.

Source: ClinicalTrials.gov · NCT07215533 · Locations: New York